background: precocious puberty, as early physical development and low final height might lead to psychosocial problems. objective: to evaluate etiology and clinical feature of precocious puberty in a cohort of iranian children. materials and methods: in this case-series study, 44 girls and 8 boys with precocious puberty referred to endocrine reserch centre (firouzgar), institute of endocrinolog...

background: prematurity is the main cause of death in infants under one years of age and is the main reason for nicu hospitalization. the stressful environment of nicu exposes preterm infants to inappropriate stimuli. this study aimed to determine and compare the mean of heart rate and oxygen saturation of premature infants before and during a designed program in nicu. methods: in a clinical tr...

background: feeding intolerance is a common problem among premature infants. there is limited information on the safety and effects of oral probiotic supplements, especially products containing lactobacillus reuteri, and the incidence of necrotizing enterocolitis (nec) in low birth weight preterm infants. this study aimed to evaluate the effects of lactobacillus reuteri on the gastrointestinal ...

BACKGROUND Premature clopidogrel discontinuation after drug-eluting stent placement is associated with adverse outcomes. Little is known about patient and hospital factors associated with premature discontinuation or whether less variation in premature discontinuation exists in integrated health care systems such as the Veterans Affairs (VA). METHODS AND RESULTS We evaluated the frequency of ...

Background: Premature birth is a major cause of infant mortality in developed countries. Newborns confined to neonatal intensive care units (NICUs) are in a rapid stage of brain development. As such, sleep plays a pivotal role in the proper brain development of newborns. However, this developmental aspect is often disregarded due to the lack of information. Aim: This study aimed to evaluate the...