BACKGROUND AND PURPOSE During diabetes, expression of inducible nitric oxide synthase (iNOS) plays an important role in the development of endothelial dysfunction in extracranial blood vessels. Progression of vascular dysfunction after the onset of diabetes differs among vascular beds. In this study, the effects of hyperglycemia/diabetes on vasomotor function were examined in cerebral arteriole...

The paper is devoted to the application of machine learning methods prediction development gestational diabetes mellitus in early pregnancy. Based on two publicly available databases, study assesses influence such features as body mass index, thickness triceps skin folds, ultrasound measurements maternal visceral fat, first measured fasting glucose, and others a predictors mellitus. supervised ...

Diabetes mellitus (DM) is the leading cause of the end-stage renal disease (ESRD). Vascular diseases are the most common cause of morbidity and mortality in the chronic kidney disease. The aim of this study was to analyze the impact of peritoneal dialysis (PD) treatment on morphologic and hemodynamic vascular parameters of carotid arteries in diabetic type 2 and nondiabetic patients with ESRD d...

BACKGROUND/AIMS This study aimed to investigate whether the apolipoprotein (Apo) B/ApoA-I ratio is associated with carotid intima-media thickness (CIMT) in type 2 diabetes mellitus (T2DM) subjects with low density lipoprotein cholesterol (LDL-C) levels less than 100 mg/dL. METHODS This cross-sectional study included 845 subjects aged with T2DM 40 to 75 years who had visited Huh's Diabetes Cen...

Preterm birth (PTB, <37 weeks) may be a marker of endothelial dysfunction and a proinflammatory phenotype; both are risk factors for cardiovascular disease. We studied 916 women (46% black) with 1181 live births between enrollment in the Coronary Artery Risk Development in Young Adults study (age 18-30 years) and 20 years later. C-reactive protein was measured at years 7, 15, and 20. Interleuki...

UNLABELLED BACKGROUND AND PURPOSE-To investigate relationships among plaque formation, increasing intima-media thickness, and age, we examined ultrasonographically carotid arteries of subjects who had no major atherosclerotic risk factors and who ranged in age from young adults to centenarians. METHODS We studied 319 healthy subjects (154 men, 165 women; age range, 21 to 105 years) with no hi...

BACKGROUND The present study aimed to investigate the prevalence and risk factors for extracranial carotid artery stenosis (ECAS) and intracranial carotid artery stenosis (ICAS) simultaneously in asymptomatic Chinese pure rural population. METHODS We analyzed 2589 asymptomatic subjects aged over 30 yr. by ultrasonography and transcranial Doppler simultaneously in 13 isolated villages by door-...

Introduction:In this study, a non-invasive method based on consecutive ultrasonic image processing is introduced to assess time rate changes of the carotid artery wall displacement, velocity and acceleration in the longitudinal direction. The application of these parameters to discriminate healthy and atherosclerotic arteries was evaluated. Methods:Longitudinal displacement rate of common ...

P a t i e n t s 20 536 patients who were 40 to 80 years of age (28% were ≥ 70 y of age, 75% men); had nonfasting total cholesterol levels ≥ 3.5 mmol/L; and had a substantial 5-year risk for death because of a history of coronary heart disease (CHD), occlusive disease of noncoronary arteries, or diabetes mellitus or a history of treated hypertension (in men ≥ 65 y of age). Exclusion criteria inc...