Dopamine (DA) D3 and D2 receptor mechanisms are implicated in cocaine's abuse-related behavioral effects, but the relative contribution of the two receptor subtypes is only partially characterized. This study investigated the role of D3 and D2 subtype mechanisms by determining the degree to which the D3-preferring antagonist PG01037 [N-{4-[4-(2,3-dichlorophenyl)-piperazin- 1-yl]-trans-but-2-eny...

Today, as a result of the changes in social, cultural and family life with globalization, demands needs people have also changed. Due to reasons such lifestyle, shrinkage family, individualization single-person living style, residences been reduced spatially production 'studio flats', most common types small produced 1+0, 1+1, 2+1, has increased today. The focus this study is suitability housin...

This research is concerned with the phenomenon of semantic change, which one phenomena development that modern linguists have been interested in a lot by showing it to ancient Arab linguists, especially exegetes Holy Qur’an, including Al-Qurtubi, who field this research. The was (the change terms specifying or expanding meaning), general connotation limited some its parts and comprehensiveness ...

OBJECTIVES The objective of this study was to determine whether physicians' treatment preferences are influenced by patients' age. METHODS We mailed a survey to a random sample of rheumatologists practicing in the US. The survey included a scenario describing a hypothetical patient with rheumatoid arthritis (RA) on hydroxychloroquine, sulfasalazine and low-dose prednisolone, who presents with...

BACKGROUND Approximately 20% of the US population primarily speaks a language other than English at home. Yet the effect of language preference on treatment of acute ischemic stroke (AIS) patients remains unknown. We aimed to evaluate the influence of language preference on AIS patients' receipt of intravenous (IV) thrombolysis. METHODS AND RESULTS We analyzed data from 3894 AIS patients who ...