This paper introduces Latent Growth Modeling (LGM) as a feasible method for analyzing longitudinal data to understand the process of change over time. Given the need to go beyond cross-sectional models, explore longitudinal Information Systems (IS) phenomena, and test IS theories over time, LGM is proposed as a complementary method to help IS researchers propose and evaluate time-centric hypoth...

To obtain sorting algorithms that scale to the largest available machines, conventional parallel sorting algorithms cannot be used since they either have prohibitive communication volume or prohibitive critical path length for computation. We outline ideas how to combine a number of basic algorithmic techniques which overcome these bottlenecks.

Diabetes mellitus is a major health problem associated with microvascular and macrovascular complications, leading to increased morbidity and mortality. It is rapidly growing worldwide with a huge economical and social burden. Although prevention and treatment of diabetes and its complications play a key role in reducing its morbidity and mortality, they require an integrated team approach at n...

Male reproductive processes in flowering plants take place in the stamen (Esau, 1977). This sporophytic organ system contains diploid cells that undergo meiosis and produce haploid male spores, or microspores. Microspores divide mitotically and differentiate into multicellular male gametophytes, or pollen grains, that contain the sperm cells. Figures 1 and 2 show that the stamen consists of two...

The simple reason is that the field moves at a rapid pace, which still seems to be accelerating instead of slowing down. Therefore, both researchers and clinicians are constantly faced with new pathophysiological concepts, new drugs and new therapeutic frontiers. The field of pulmonary hypertension is large and encompasses a broad range of diseases and conditions affecting hundreds of thousands...

Hyponatremia is the most common electrolyte imbalance in hospitalized patients. It is associated with several unfavorable endpoints such as: the need for intensive care, longer hospital stay, higher hospitalization costs, discharge to long-term care facilities, and mortality. It is still not clear if there is a direct causal relationship or if hyponatremia is simply a marker of disease severity...

1Division of Rheumatology and Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA 2Department of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA 3Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA 4Department of Medicine/ Rheumatolog...