BACKGROUND Food allergies are perceived as a significant problem in school environments; as a result, a teacher's ability to recognise and deal with allergic reactions is of fundamental importance to protect children's health. This paper includes the results of a study conducted for the purposes of designing, implementing and monitoring a specific set of teacher-oriented communication actions. ...

It has been well established that complex mixtures of phytochemicals in fruits and vegetables can be beneficial for human health. Moreover, it is becoming increasingly apparent that phytochemicals can influence the pharmacological activity of drugs by modifying their absorption characteristics through interactions with drug transporters as well as drug-metabolizing enzyme systems. Such effects ...

Recent research has demonstrated that consumption of food -especially fruits and vegetables- can alter the effects of drugs by interfering either with their pharmacokinetic or pharmacodynamic processes. Despite the recognition of such drug-food associations as an important element for successful therapeutic interventions, a systematic approach for identifying, predicting and preventing potentia...

Download pose: Several recent oral oncology drugs were labeled for administration in fasted states despite the at food increases their bioavailability. Because this was inconsistent with the principles of oral drug ry, we hypothesized that there were inconsistencies across therapeutic areas. erimental Design: Oral agents approved by the U.S. Food and Drug Administration from January to May 2009...

A multiplex RT-qPCR was developed to examine CYP1A2, CYP2D6, and CYP3A4 induction properties of compounds from food and herbal sources. The induction of drug metabolizing enzymes is an important pharmacokinetic interaction with unique features in comparison with inhibition of metabolizing enzymes. Cytochrome induction can lead to serious drug-drug or drug-food interactions, especially if the co...

INTRODUCTION Studies on bioavailability are part of the clinical development of drugs for oral use in order to identify potential drug-food interactions. For oral antitumor drugs, their clinical importance is currently recognized although regrettably the information available presents variability concerning the scientific evidence. OBJECTIVES To review the available scientific evidence about ...

Findings Average age of the patients in this study is 69.21(43-80) and %64.3 of them are females. Of the patients who have participated in the study %30.8 of them have stage III, %69.2 of them have stage IV HF. After their diagnosis, patients have been in intensive care for an average of 6.7 ± 4.4 (1-16) times. Average time period for the disease is 9.4 ± 7.5 years. In this study 3 categories f...