background:  about 75% of the symptomatic patients who involved with endometriosis have pelvic pain and dysmenorrhea. pentoxifyllin is one of the drugs that according to its mechanism could be effective for pain relief of endometriosis which has been used for endometriosis treatment recently   objective: we conducted a comparative study for detecting the effect of pentoxifylin (as an immonomode...

15 Tonic pain after injury characterises a behavioural state that prioritises recovery. Although generally 16 suppressing cognition and attention, tonic pain needs to allow effective relief learning to reduce 17 the cause of the pain. Here, we describe a central learning circuit that supports learning of relief 18 and concurrently suppresses the level of ongoing pain. We used computational mode...

Tonic pain after injury characterises a behavioural state that prioritises recovery. Although generally suppressing cognition and attention, tonic pain needs to allow effective relief learning to reduce the cause of the pain. Here, we describe a central learning circuit that supports learning of relief and concurrently suppresses the level of ongoing pain. We used computational modelling of beh...

All products derived from the Cannabis sativa plant are referred to as cannabis, including two highly active cannabinoids, cannabidiol (CBD) and tetrahydrocannabinol (THC). Unlike THC, CBD is not psychoactive, which makes an appealing option for those seeking pain relief without THC's “high” or potential abuse dependence. Despite lack of FDA approval, oil gaining popularity a remedy chronic pai...