نتایج جستجو برای: postnatal exposure

تعداد نتایج: 336832  

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
Alexandra Veyrac Julie Bakker

Neurons incorporated into the adult main olfactory bulb (MOB) and accessory olfactory bulb (AOB) derive from the subventricular zone (SVZ). Despite some recent studies on the role of olfactory neurogenesis in sociosexual behaviors mediated by hormones, data on the implication of estrogens are still lacking. Taking advantage of female aromatase-knockout (ArKO) mice, which are unable to produce e...

2017
Hein M. Tun Theodore Konya Tim K. Takaro Jeffrey R. Brook Radha Chari Catherine J. Field David S. Guttman Allan B. Becker Piush J. Mandhane Stuart E. Turvey Padmaja Subbarao Malcolm R. Sears James A. Scott Anita L. Kozyrskyj M. R. Sears P. Subbarao S. S. Anand M. Azad A. B. Becker A. D. Befus M. Brauer J. R. Brook E. Chen M. Cyr D. Daley S. Dell J. A. Denburg Q. Duan T. Eiwegger H. Grasemann K. HayGlass R. Hegele D. L. Holness P. Hystad M. S. Kobor T. R. Kollmann A. L. Kozyrskyj C. Laprise W. Y. W. Lou J. Macri P. M. Mandhane G. Miller T. Moraes P. D. Paré C. Ramsey F. Ratjen A. Sandford J. A. Scott J. Scott F. Silverman E. Simons T. Takaro S. Tebbutt T. To S. E. Turvey

BACKGROUND Early-life exposure to household pets has the capacity to reduce risk for overweight and allergic disease, especially following caesarean delivery. Since there is some evidence that pets also alter the gut microbial composition of infants, changes to the gut microbiome are putative pathways by which pet exposure can reduce these risks to health. To investigate the impact of pre- and ...

2016
Rucheng Chen Xiaoqiao Tang Bolin Fan Jiafa Liu Xudong Jia Xiaoguang Yang Takuma Kato

The role of maternal allergen exposure in the allergenicity of the offspring remains controversial. Some studies have shown that maternal exposure is a risk factor for allergy in the offspring, whereas other studies have shown that maternal exposure induces immune tolerance and protects offspring from allergy disease. Therefore, we utilized maternal rat allergen exposure model to evaluate the o...

2006
Paul W. Stewart David M. Sargent Jacqueline Reihman Brooks B. Gump Edward Lonky Thomas Darvill Heraline Hicks James Pagano

BACKGROUND Animal studies have shown that exposure to common, low-level environmental contaminants [e.g., polychlorinated biphenyls (PCBs), lead] causes excessive and inappropriate responding on intermittent reinforcement schedules. The Differential Reinforcement of Low Rates task (DRL) has been shown to be especially sensitive to low-level PCB exposure in monkeys. OBJECTIVES We investigated ...

2012
Annet F. M. van Abeelen Sjoerd G. Elias Tessa J. Roseboom Patrick M. M. Bossuyt Yvonne T. van der Schouw Diederick E. Grobbee Cuno S. P. M. Uiterwaal

Objective. To examine the association between undernutrition during postnatal periods of development and the risk of overweight in adulthood. Methods. We studied 8,091 women from Prospect-EPIC, exposed to the Dutch famine at ages between 0 and 21 years, recruited at ages between 49 and 70 years. We used linear and logistic regression models to explore the effect of famine on BMI, waist circumfe...

2016
S Finer M S Iqbal R Lowe B W Ogunkolade S Pervin C Mathews M Smart D S Alam G A Hitman

OBJECTIVES Famine exposure in utero can 'programme' an individual towards type 2 diabetes and obesity in later life. We sought to identify, (1) whether Bangladeshis exposed to famine during developmental life are programmed towards diabetes and obesity, (2) whether this programming was specific to gestational or postnatal exposure windows and (3) whether epigenetic differences were associated w...

Journal: :Environmental Health Perspectives 1990
K N Dietrich P A Succop R L Bornschein K M Krafft O Berger P B Hammond C R Buncher

A prospective methodology was used to assess the neurobehavioral effects of fetal and postnatal lead exposure during the first 2 years of life. Lead was measured in whole blood prenatally in mothers and at quarterly intervals in the infant. Prenatal blood lead levels were low (mean = 8.0 micrograms/dL). However, approximately 25% of the study infants had at least one serial blood lead level of ...

Journal: :Alcoholism, clinical and experimental research 2013
Jarrod M Ellingson Wendy S Slutske Leah S Richmond-Rakerd Nicholas G Martin

BACKGROUND There are robust sex differences for alcohol phenotypes, with men reporting more drinking and alcohol use disorder (AUD) symptoms than women. However, the sources of these effects are not completely understood. Sex hormones, a substantial biological sex difference, exert neurobehavioral influences and are candidates for influencing sex differences in alcohol phenotypes. This study in...

Journal: :Investigative ophthalmology & visual science 2002
Olga Dembinska Luz Marina Rojas Sylvain Chemtob Pierre Lachapelle

PURPOSE Findings in a previous study have shown that the retina of newborn rats exposed to hyperoxia during the first days of life sustain permanent functional (as determined with the rod ERG) and structural (as determined with histology) damage that appears to be determined by the level of retinal maturity reached at the time of oxygen exposure-the retinas of rat pups being more susceptible to...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز 1381

‏‎the hypothesis is that recent and frequent exposure to lexical items leads to a more fluent production of speech in terms of rate of speech. to test the hypothesis , a one- way anova experimental design was carried out. 24 senior student of efl participated in a one-way interview test. data analyses revealed that those who were exposed frequently to the lexical items over a week prior to inte...

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