Accommodation may be restored to presbyopic lenses by refilling the lens capsular bag with a soft polymer. After this accommodative lens refilling prevention of capsular opacification is a requirement, since capsular opacification leads to a decreased clarity of the refilled lens. It has been hypothesized that capsular fibrosis causing the capsular opacification results in increased stiffness o...

OBJECTIVE Reported rates of posterior capsule opacification (PCO) vary widely and are based on various definitions of PCO, varying lengths and intervals of follow-up, and the use of different surgical techniques, intraocular lens (i.o.l.) designs, and methods of IOL implantation. This study was designed to obtain a more precise overall estimate of the incidence of PCO and to explore factors tha...

BACKGROUND The aim of this study was to develop a system of computerised analysis of digital images of posterior capsule opacification (PCO) that is evidence based, objective and freely available. The paper will present evidence for the reliability and validity of the developed system. METHODS The system of PCO analysis was developed considering current published evidence on visual significan...

PURPOSE To describe a new method of measuring posterior capsule opacification (PCO) and intraocular lens (IOL) rotation and report the validation of the method. SETTING Ophthalmology Department, St. Thomas' Hospital, and Medical Imaging, Department of Physics, King's College, London, United Kingdom. METHOD A new interactive software program, POCOman, was developed for the semiobjective asse...

PURPOSE To investigate how posterior capsule opacification (PCO) affects visual function in pseudophakic eyes. METHODS One hundred and six eyes that had undergone uncomplicated phacoemulsification were recruited sequentially. Patients with surgical complications or other ocular disease were excluded. PCO was assessed by a digital retroillumination camera using a software program based on the ...

OBJECTIVE Surface roughness parameters of various intraocular lenses (IOLs) biomaterials using atomic force microscopy (AFM) are compared. Variation, if any, in the micro-roughness properties of different IOLs made up of the same biomaterial is also explored. Retrospective analysis of posterior capsular opacification (PCO) incidence has been followed up for a period of four years post IOL impla...

Modern cataract surgery with implantation of an intraocular lens (IOL) is an increasingly safe and successful procedure, though complications still occur. This thesis addresses the most common complication, posterior capsule opacification (PCO) and the rare but serious complication postoperative endophthalmitis (POE). The pathogenesis of PCO is multifactorial and several surgical and IOL-relate...

This thesis examined the incidence and factors affecting the rate o f posterior capsular opacification (PCO), the most com mon complication o f cataract surgery, in diabetic and uveitic patients and in patients with multifocal intraocular lenses (IO L s). These patients are particularly sensitive to PCO developm ent because o f the risks associated with Nd:Y AG capsulotom y in the former two gr...