BACKGROUND Haptocorrin (HC) carries the major part of circulating cobalamin, but whether HC is altered on treatment with vitamin B12 remains unknown. METHODS Our study included 3 populations: a population of vegan men (n = 174; vegan population), of whom 63 were treated daily with 5 mg of oral vitamin B12 for 3 months; a group of patients with a previous methylmalonic acid (MMA) concentration...

A challenge in the field of ecotoxicology is the linkage of alterations at molecular and biochemical levels of organization to adverse outcomes in individuals and populations. In the present study, a predictive relationship between plasma vitellogenin (VTG) concentration and fecundity in female fathead minnows (Pimephales promelas) was derived from 21-d laboratory toxicity tests with five chemi...

it was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (ap). it seems that some other types of mechanisms must be involved in ap propagation. in this article, we...

Using suspension-cultured Acer pseudoplatanus cells requiring 2,4-dichlorophenoxyacetic acid for growth, the dependence of the population doubling time and the maximum increase in cell population density on the auxin concentration was studied. It appears that in the range of 2,4-dichlorophenoxyacetic acid concentration from 4 x 10(-8) to 4 x 10(-6) M, the rate of cell division during the logari...

Bath application of the GABAB receptor agonist baclofen produced a concentration-dependent long-lasting potentiation (LLP) of the evoked population spike in the dentate gyrus of rat hippocampal slices. A high concentration of baclofen (5 microM) also produced a loss of inhibition that was manifested as the appearance of epileptiform, multiple evoked population spikes and a decrease in paired-pu...

to assess the environmental radioactivity levels and hence to determine the population exposure in kutubdia island, bangladesh the sediment samples were analyzed by using gamma ray spectrometry. in those sediment samples the average activity concentration of natural radionuclides 238u, 232th and 40k were found 15.39±1.67, 38.35±0.76 and 475.51±21.15 bq/kg respectively. the activity concentratio...

OBJECTIVE To examine the value of glycated haemoglobin (HbA(1c)) concentration, a marker of blood glucose concentration, as a predictor of death from cardiovascular and all causes in men. DESIGN Prospective population study. SETTING Norfolk cohort of European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk). SUBJECTS 4662 men aged 45-79 years who had had glycated haemogl...

Population-level effects of the mysid, Americamysis bahia, exposed to varying thiobencarb concentrations were estimated using stage-structured matrix models. A deterministic density-independent matrix model estimated the decrease in population growth rate (lambda) with increasing thiobencarb concentration. An elasticity analysis determined that survival of middle stages provided the largest con...

The goals of this study were: (I) to report the helminth population in cattle, sheep and goats; (II) to determine the concentration and diversity of the population; and (III) to study the role of host age, host sex, diet and season in structuring the population. A total of 485 cattle, 1144 sheep and 989 goats were examined for helminth population for four seasons. The helminth population consis...