drawbacks, such as increasing the dosage, the administration frequency and the resultant occurrence of side effects. Furthermore, as the rate-limiting step in the absorption process for poorly water-soluble drugs is the dissolution rate of such drugs in the gastrointestinal fluids rather than the rapidity of their diffusion across the gut wall, it is important to improve the oral bioavailabilit...

Self-emulsifying drug delivery systems (SNEDDS) are highly in quest due to their innumerable benefits like better portability, improved stability and higher drug loading, coupled with ease and economy of their production. SNEDDS are used to improve the solubility of high lipophilic drugs. SNEDDS are improving the oral bioavailability of limited water-soluble drug compounds. These SNEDDS are iso...

Poor solubility is a well-recognized property of many drug molecules [1]. Unprotected administration of poorly water-soluble drugs is problematic. Aggregation, precipitation, uncontrolled binding, and direct exposure to a harsh biological environment render this process inefficient. The putative ‘solution’ of using higher drug concentrations narrows the window between a therapeutic success and ...