Objective: Pioglitazone is one of the oral medications of type 2 diabetes (T2DM). The purpose of this study was to evaluate the effect of pioglitazone on asthma and diabetes treatment outcomes among patients with concurrent asthma and T2DM. Materials and Methods: We conducted a quasi-experimental study on 11 patients with concurrent asthma and T2DM in Yazd Afshar Hospital and Yazd diabetic res...

asthma is one of the most common chronic diseases of childhood. inhaled corticosteroids (ics) are the recommended controller drug for asthma treatment. the aim of our study was to determine concerns and fears of parents of children with asthma towards the use of ics. one hundred parents of asthmatic children were interviewed using structural questionnaire. airway inflammation was reported by on...

BACKGROUND In many patients with mild asthma, the low frequency of symptoms and the episodic nature of exacerbations make adherence to regular maintenance treatment difficult. This often leads to over-reliance on short-acting β2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations. The use...

In adults fatal and near-fatal asthma have similar clinical characteristics. Therefore, near-fatal asthma in adults can be used as a model for fatal asthma. A nationwide study on fatal and near-fatal asthma in children <16 yrs was performed in order to assess whether, as in adults, near-fatal asthma can be used as a model for fatal asthma. From 1996 to 1998, all paediatric hospitals and paediat...

assesment of health related quality of life (hrql) is increasingly recognized as an important part of the patient care in asthma. we aimed to evaluate the effect of personality disorders (pds) on hrql and the severity of disease in asthmatic patients. ninety seven consecutive patients with asthma and ninety healthy controls were included. all  patients  completed  a  short  form-36  health  sur...

A systematic review of English and Korean articles published between 1990 and 2004 and a search of database and various online resources was conducted to determine the prevalences, mortality rates, socioeconomic burden, quality of life, and treatment pattern of asthma in Korean adults and children. Asthma morbidity and mortality in Korea are steadily increasing. The prevalence of asthma in Kore...

U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical companies and six patient organisations with the objective of improving the understanding of asthma disease mechanisms using a systems biology approach.This cross-sectional assessment of adults with severe asthma, mild/moderate asthma and healthy controls from 11 European countries consisted of analyses of p...

Childhood asthma is a highly morbid respiratory disorder. In spite of effective remedies, heterogeneity of disease process and poor treatment compliance lead to substantial proportion of childhood asthma remaining uncontrolled. Hence, school absenteeism, loss of play hours and sleep disturbances are significant. Strain on health care budget is also high. Newer immunotherapeutic modalities do of...

Several studies suggested an association between the regular use of β2-agonists and asthma deaths. Whether this association represents adverse effects of β-agonist use or is entirely due to disease severity is a matter of ongoing debate. Previous literature indicates that confounding by poor asthma control may explain the apparent deleterious effects of inhaled β2-agonists. Tolerance to nonbron...

In paediatric Asthma, involvement of caregivers is essential, therefore a satisfactory level parental knowledge influences the effectiveness treatment bronchial asthma as an important part in prevention exacerbations and complications hypothesis this research that good about among asthmatic children's can lead to better control asthma.