Background: Diabetes mellitus is a prevalent metabolic disorder worldwide; its incidents have grown notably in recent years. Over the last 50 years, lifestyle changes led to dramatic increase prevalence of type 2 diabetes around world. India has been projected as diabetic capital and complications pose major threat future public health resources throughout world are cause blindness, kidney fail...

Tretinoin is the most effective available topical comedolytic agent, but topical application may lead to erythema, peeling and burning of the skin. During the past few decades many reports have documented an emergence of antibiotic resistance by Propionibacterium acnes during treatment of acne. Furthermore, systemic antimicrobials used in the treatment of acne have been causally associated with...

Diabetes mellitus, a metabolic disorder, is characterized by hyperglycemia and altered metabolism. The administration of D-Nil plus (a polyherbal drug) showed effective treatment for alloxan induced diabetes in rats. In diabetic rats, haematological profiles namely RBC, WBC, platlet count and haemoglobin were decreased whereas ESR was increased. Similarly biochemical parameters creatinine, urea...

Tuberculosis (TB) is a communicative disease caused by Mycobacterium tuberculosis bacteria that may cause death if it is left untreated. WHO (2010) recommended standard drugs as first line anti-tuberculosis (anti-TB) therapy involved (HRZE): isoniazid (H), rifampicin (R), pyrazinamide (Z) and ethambutol (E) received as a fixed dose combination suspension according to the body weight. However, h...

An experiemental study was conducted in day old 150 VenCobb chicks to evaluate efficacy of polyherbal formulation in induced bacterial enteritis with Salmonella enteritidis. Birds were randomly divided into three groups: negative control, infected and untreated control & prophylactically treated group with AV/ ADC/16 (14th-28th days). Salmonella infection was induced on day 21st. A significant ...

Materials and methods CWR22Rv1 cells (a castrate-resistant human PCa cell line) were treated with a polyherbal mixture of botanicals (PHBs) consisting of 10 herbal extracts [1] and we investigated whether inhibition of cell proliferation was linked to the activity of 5’adenosine monophosphate (AMP)activated protein kinase (AMPK), a potential tumor suppressor protein that functions as a central ...

"Cinkara", a polyherbal preparation reduced pentobarbitone induced hypnosis in mice, decreased apomorphine induced fighting, aggression and stereotypy and increased amphetamine induced aggregated toxicity in mice. It also increased immobility of rats in forced swimming test, an action which was not blocked by chlor-promazine, and increased ambulation in open arena test. It did not modify electr...