The Hengduan Mountains region (HMR) on the southeastern Tibetan Plateau, supports a high diversity of herbs, particularly in its subalpine to alpine ecosystems, due altitude and cool temperate climate. Current understanding formation such herbaceous richness is based chiefly molecular phylogenies; however, direct geological evidence lacking because herbs are rarely preserved as macroscopic foss...

Recently, drug resistance due to the extensive abuse and over-use of antibiotics has become an increasingly serious problem, making the development of alternative antibiotics a very urgent issue. In this study, the Chinese herbal medicine, Polygonum cuspidatum, was extracted with 95% ethanol and the crude extracts were further purified by partition based on solvent polarity. The antimicrobial a...

Eighty-seven methanol extracts of medicinal plants, most of them are currently used in Vietnamese oriental medicine, were screened for NF-κB inhibitory activity. Seven methanol extracts showed strong to moderate inhibitory activity. These include the extracts of Crinum latifolium (leaves), Evodia rutaecarpa (fruits), Polygonum cuspidatum (rhizoma), Perilla ocymoides (leaves), Rubia cordifolia (...

BACKGROUND Resveratrol have been shown to exert an antiinflammatory and antiaging effects in vitro and in animal models. OBJECTIVE The objective of the study was to investigate the effect of a Polygonum cuspidatum extract (PCE) containing resveratrol on oxidative and inflammatory stress in normal subjects. RESEARCH DESIGN AND METHODS Two groups (10 each) of normal-weight healthy subjects we...

The lack of effective therapeutics for Coxsackievirus B₄ (CVB₄) infection underscores the importance of finding novel antiviral compounds. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is one of the natural anthraquinone derivatives obtained from the root and rhizome of Polygonum cuspidatum. In the present study, the possibility of using emodin as a potential antiviral to treat CVB₄ infection...

The genus Rhinoncomimus Wagner, 1940 includes seven species from Eastern Asia. One new species, Rh. continuus sp. nov. from Yunnan, China, is described. Habitus photos, illustrations and descriptions of all species except Rh. rubripes Korotyaev, 2006 (a possible junior synonym of R. niger Chûjô and Morimoto, 1959) are provided in detail, as well as key to species and distribution maps. In addit...