نتایج جستجو برای: polycythemia vera

تعداد نتایج: 10734  

Journal: :Haematologica 2012
Alberto Alvarez-Larrán Agueda Ancochea Anna Angona Carme Pedro Francesc García-Pallarols Luz Martínez-Avilés Beatriz Bellosillo Carlos Besses

The cut off for hemoglobin or hematocrit that indicates the need for an isotopic red cell mass study was investigated in 179 patients with a presumptive diagnosis of polycythemia vera or essential thrombocythemia. Hematocrit showed better diagnostic accuracy than hemoglobin. Hemoglobin over 18.5 g/dL in males or over 16.5 g/dL in females showed a high specificity indicating that red cell mass s...

Journal: :Haematologica 2012
Susanne Schnittger Ulrike Bacher Christiane Eder Frank Dicker Tamara Alpermann Vera Grossmann Alexander Kohlmann Wolfgang Kern Claudia Haferlach Torsten Haferlach

We investigated 15,542 patients with suspected BCR-ABL1- negative myeloproliferative or myelodysplastic/myeloproliferative neoplasm (including 359 chronic myelomonocytic leukemia) by a molecular marker set. JAK2V617F was detected in the suspected categories as follows: polycythemia vera 88.3%, primary myelofibrosis 53.8%, essential thrombocythemia 50.2%, and not further classifiable myeloprolif...

2006
Sam Berger Louis M. Aledort Harriet S. Gilbert John P. Hanson Louis R. Wasserman

with varying platelet counts. Adenosine diphosphate, epinephrine, collagen, and thrombin were used as aggregating agents. Eighty-one % of the 62 studies were abnormal. The frequency of abnormal tests increased from those with normal hematocrits and platelet counts (75%) through to those with elevated hematocrits and platelet counts (100%). One hundred % of the studies in spent polycythemia vera...

Journal: :Haematologica 2011
Brady L Stein Donna M Williams Christine O'Keefe Ophelia Rogers Roxann G Ingersoll Jerry L Spivak Amit Verma Jarek P Maciejewski Michael A McDevitt Alison R Moliterno

BACKGROUND The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the same acquired genetic lesion, but the concept of JAK2 V617F serving as the sole lesion responsible for these neoplasms is under question, and there has been interest in identifying additional mutations that may contribute to disease pathogenesis. Because ASXL1 lesions ha...

Journal: :Blood 1985
B P Alter H S Gilbert

Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyur...

Journal: :Circulation 1961
D VEREL

IT IS WELL KNOWN that in polyeythemia rubra vera the total blood volume increases as the hematocrit level rises beyond approximately 55 per cent.1-2 This increase masks the extent of the polycythemia and insures that the plasma volume is not greatly diminished despite an increase in red cell volume to twice or three times the normal value. The changes in adults suffering from cyanotic congenita...

2014
Yong Sik Lee Byung Ho Seo Soo Won Lee Sung Hwan Kim Byung Kil Ahn

A 68-year-old woman who suffered from polycythemia vera presented at our clinic with the chief complaints of pain, swelling, and a warm sensation in her left thigh. She had undergone a left bipolar hemiarthroplasty following a hip fracture 24 days prior to this presentation. Her erythrocyte sedimentation rate and C-reactive protein (CRP) levels were elevated. In addition, a postoperative infect...

Journal: :Mayo Clinic proceedings 2005
Ayalew Tefferi Tiziano Barbui

Essential thrombocythemia, polycythemia vera, and myelofibrosis with myeloid metaplasia constitute the "classic" bcr/abl-negative myeloproliferative disorders (MPDs). Each of these MPDs represents a stem cell-derived clonal myeloproliferation with the respective features of thrombocytosis, erythrocytosis, and bone marrow fibrosis. Unlike with cases of chronic myeloid leukemia, in which the bcr/...

2017
Renbo Guo Yiran Liang Lei Yan Zhonghua Xu Juchao Ren

BACKGROUND Erythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma. CASE PRESENTATION We report a case of a young man suffering from a giant (22-cm) mass on his left kidney. Because of a history of polycythemia vera, the patient had been treated for the condi...

Journal: :The American journal of cardiology 1971
A Rosenthal L N Button D G Nathan O S Miettinen A S Nadas

IT IS WELL KNOWN that in polyeythemia rubra vera the total blood volume increases as the hematocrit level rises beyond approximately 55 per cent.1-2 This increase masks the extent of the polycythemia and insures that the plasma volume is not greatly diminished despite an increase in red cell volume to twice or three times the normal value. The changes in adults suffering from cyanotic congenita...

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