نتایج جستجو برای: polycythemia vera
تعداد نتایج: 10734 فیلتر نتایج به سال:
The cut off for hemoglobin or hematocrit that indicates the need for an isotopic red cell mass study was investigated in 179 patients with a presumptive diagnosis of polycythemia vera or essential thrombocythemia. Hematocrit showed better diagnostic accuracy than hemoglobin. Hemoglobin over 18.5 g/dL in males or over 16.5 g/dL in females showed a high specificity indicating that red cell mass s...
We investigated 15,542 patients with suspected BCR-ABL1- negative myeloproliferative or myelodysplastic/myeloproliferative neoplasm (including 359 chronic myelomonocytic leukemia) by a molecular marker set. JAK2V617F was detected in the suspected categories as follows: polycythemia vera 88.3%, primary myelofibrosis 53.8%, essential thrombocythemia 50.2%, and not further classifiable myeloprolif...
with varying platelet counts. Adenosine diphosphate, epinephrine, collagen, and thrombin were used as aggregating agents. Eighty-one % of the 62 studies were abnormal. The frequency of abnormal tests increased from those with normal hematocrits and platelet counts (75%) through to those with elevated hematocrits and platelet counts (100%). One hundred % of the studies in spent polycythemia vera...
BACKGROUND The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the same acquired genetic lesion, but the concept of JAK2 V617F serving as the sole lesion responsible for these neoplasms is under question, and there has been interest in identifying additional mutations that may contribute to disease pathogenesis. Because ASXL1 lesions ha...
Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyur...
IT IS WELL KNOWN that in polyeythemia rubra vera the total blood volume increases as the hematocrit level rises beyond approximately 55 per cent.1-2 This increase masks the extent of the polycythemia and insures that the plasma volume is not greatly diminished despite an increase in red cell volume to twice or three times the normal value. The changes in adults suffering from cyanotic congenita...
A 68-year-old woman who suffered from polycythemia vera presented at our clinic with the chief complaints of pain, swelling, and a warm sensation in her left thigh. She had undergone a left bipolar hemiarthroplasty following a hip fracture 24 days prior to this presentation. Her erythrocyte sedimentation rate and C-reactive protein (CRP) levels were elevated. In addition, a postoperative infect...
Essential thrombocythemia, polycythemia vera, and myelofibrosis with myeloid metaplasia constitute the "classic" bcr/abl-negative myeloproliferative disorders (MPDs). Each of these MPDs represents a stem cell-derived clonal myeloproliferation with the respective features of thrombocytosis, erythrocytosis, and bone marrow fibrosis. Unlike with cases of chronic myeloid leukemia, in which the bcr/...
BACKGROUND Erythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma. CASE PRESENTATION We report a case of a young man suffering from a giant (22-cm) mass on his left kidney. Because of a history of polycythemia vera, the patient had been treated for the condi...
IT IS WELL KNOWN that in polyeythemia rubra vera the total blood volume increases as the hematocrit level rises beyond approximately 55 per cent.1-2 This increase masks the extent of the polycythemia and insures that the plasma volume is not greatly diminished despite an increase in red cell volume to twice or three times the normal value. The changes in adults suffering from cyanotic congenita...
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