CMS, core-multishell; NR, Nile red; MTX, methotrexate; mPEG, methoxypoly(ethylene glycol); PG, polyglycerol; dPG, dendritic polyglycerol; PEG, poly(ethylene glycol); CMS-mPEG, coremultishell nanocarrier with a mPEG outer shell; EPR, enhanced permeation and retention; PG[G1], polyglycerol dendron of generation 1; PG[G2], polyglycerol dendron of generation 2; CMS-G1, core-multishell nanocarrier w...

Long-circulating drug carriers are highly desirable in drug delivery system. However, nonspecific protein adsorption leaves a great challenge in drug delivery of intravenous administration and significantly affects both the pharmacokinetic profiles of the carrier and drugs, resulting in negatively affect of therapeutic efficiency. Therefore, it is important to make surface modification of drug ...

Three-dimensional silicon carbide-based frameworks with hierarchical micro-, meso-, and macroporous structures (3MPSiC) were prepared by a template method with subsequent carbonization via an aerosol spray drying method. The micropores were derived from partial vaporization of Si atoms during the carbonization process, whereas the meso- and macropores were generated by self-assembly of the stru...

Linear–dendrite copolymers containing hyper branched poly(citric acid) and linear poly(ethylene glycol) blocks PCA–PEG–PCA are promising nonmaterial to use  in nanomedicine. To investigate their potential application in biological systems (especially for drug carries) ONIOM2 calculations were applied to study the nature of particular interactions between drug and the polymeric nanoparticle...

Poly(ethylene glycol) (PEG) is a common building block for complex functional molecules. Because of its chain flexibility and hydrophilicity, it is widely used in bioconjugation chemistry. Modern applications require PEGs of high purity, hence well-defined, monodisperse PEG oligomers are gaining more attention. Here we report a large-scale synthetic procedure for monodisperse oligo(ethylene gly...

Atmospheric pressure plasma co-polymerization of ethylene glycol and styrene was applied to produce poly (ethylene glycol-co-styrene) using a dielectric barrier discharge. The chemical structure of polymerized films was studied by Fourier-transform infrared spectroscopy which confirms that we obtained copolymerized films with hydroxyl groups incorporated. Chemical composition of films was studi...