نتایج جستجو برای: podoplanin
تعداد نتایج: 744 فیلتر نتایج به سال:
Intralymphatic histiocytosis is a rare condition characterized by the presence of dilated lymphatic vessels containing aggregates of mononuclear histiocytes (macrophages) within their lumina. The phenomenon seems to occur almost exclusively within the reticular dermis. Although its pathogenesis remains uncertain, there has been speculation about the possible relationship between intralymphatic ...
Cancer-associated fibroblasts (CAFs) are well-known to be part of the tumor microenvironment. This heterogeneous population of cells of the tumor microenvironment via secretion of various growth factors and cytokines was shown to contribute to increased cancer cell proliferation rate, migration, invasiveness and other key processes such as angiogenesis and lymphangiogenesis. Recent studies iden...
A 23-year-old female with an established diagnosis of neurofibromatosis type 1 (NF1) was found to have two tumours in her trunk. These showed high uptake value in positron-emission/computerized tomography (PET) scans, and were suspected to be malignant peripheral nerve sheath tumours (MPNST). The extirpated tumours proved to be atypical plexiform neurofibromas. Slight to moderate podoplanin exp...
polymers, ϳ 70 mer to 250 mer, are more effective in abrogating tissue factor pathway inhibitor–anticoagulant activity. In the case of fibrin clot stabilization, polyP polymers shorter than 100 mers had no influence on fibrin clot turbidity whereas Ն 250 mer support maximal turbidity increase. Interestingly, very short phosphates, particularly PPi, effectively block the polyP-mediated enhanceme...
INTRODUCTION Previous studies have shown increased expression of stromal markers in synovial tissue (ST) of patients with established rheumatoid arthritis (RA). Here, ST expression of stromal markers in early arthritis in relationship to diagnosis and prognostic outcome was studied. METHODS ST from 56 patients included in two different early arthritis cohorts and 7 non-inflammatory controls w...
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