In the present Frontier article, we highlight recent new results on the use of platinoid complexes as therapeutic agents against Alzheimer's disease and infer the relevance of targeting monomeric soluble disordered amyloid peptides to preclude the deleterious aggregation process associated with the etiology of the disease.

Platinum metals have long been used in the glass industry for crucibles and liners because of their high melting points and their chemical inertness to most molten glasses. Contamination of glass by platinum metals has not been reported except in one or two instances where the glasses had a high content of lead or barium. It is well known that heavy lead glasses are more susceptible to colourin...

The bis-sulfoxide ligand p-tolyl-binaso and its derivatives can be used to synthesize neutral and cationic palladium and platinum complexes. Various Pt bis-sulfoxide complexes could be made by using the precursor Pt(M,SS,SS)-p-tolyl-binasoCl2 (5a) and abstracting the chlorides with silver salts. The Pd analogue of this compound (4) could not be used in the same way. In this case, the sulfoxides...

The public health benefits expected by reducing known hazardous emissions from mobile sources should not be compromised by increasing levels of other potentially hazardous unregulated emissions. Catalytic converters are going to be used to meet the statutory requirements on carbon monoxide and hydrocarbon emissions from light duty motor vehicles. Platinum and palladium metals are the catalytic ...

The design of a synthesis strategy for metal nanoparticles by templating dense microemulsions is proposed. Particle size is controlled by surfactant size rather than by microemulsion composition. The strategy was demonstrated with various systems with different surfactant: cationic, anionic and non-ionic and of different sizes. Formulations were determined using the microemulsion phase diagrams...

Carbon nanotube paper, sometimes referred to as bucky paper, is a random arrangement of carbon nanotubes meshed into a single robust structure, which can be manipulated with relative ease. Multi-walled carbon nanotubes were used to make the nanotube paper, and were subsequently modified with platinum using an electroless deposition method based on substrate enhanced electroless deposition. This...

There is a high incidence of asthma, rhinitis, conjunctivitis and contact urticaria in workers of precious metal refineries. Symptoms are closely associated with sensitization to halogenated platinum compounds, as assessed by skin-prick test. The aim of the present study was to examine the molecular mechanisms involved by describing the T-cell receptor (TCR) repertoire distribution of periphera...

Cisplatin is one of the most successful compounds in the fight against cancer. Recently, interest was directed towards the development of cisplatin analogues which possess Nheterocyclic carrier ligands, coordinated to the cytotoxic platinum(II) moiety, instead of one or both of the am(m)ines. Hydantoins form a large group of derivatives widely applied in medicine and pharmacy, especially as ant...

An important feature of biological systems to achieve complexity and precision is the involvement of multiple components where each component plays its own role and collaborates with other components. Mimicking this, we report living supramolecular polymerization achieved by collaborative assembly of two structurally dissimilar components, that is, platinum(II) complexes and poly(ethylene glyco...