نتایج جستجو برای: plasminogen activator

تعداد نتایج: 52174  

Journal: :The Journal of Experimental Medicine 1997
A. Richard Kitching Stephen R. Holdsworth Victoria A. Ploplis Edward F. Plow Désiré Collen Peter Carmeliet Peter G. Tipping

The plasminogen/plasmin system has the potential to affect the outcome of inflammatory diseases by regulating accumulation of fibrin and other matrix proteins. In human and experimental crescentic glomerulonephritis (GN), fibrin is an important mediator of glomerular injury and renal impairment. Glomerular deposition of matrix proteins is a feature of progressive disease. To study the role of p...

Journal: :The Journal of infectious diseases 1996
R B Christner M D Boyle

In this study, the role of the staphylococcal plasminogen activator, staphylokinase (SAK), was analyzed for its ability to mediate acquisition of cell-associated plasmin-like activity by staphylococci in the presence of a source of human plasminogen. A panel of staphylococcal strains isolated from humans was tested for the presence of the SAK gene, secretion of the plasminogen activator, and th...

Journal: :The Journal of biological chemistry 1964
M C DAVIES M E ENGLERT E C DERENZO

The activation of human plasminogen by streptokinase has been the subject of extensive investigation (4-8). There appears to be general agreement that at least two enzymatic activities are demonstrable in streptokinase-plasminogen reaction mixtures. One is the proteolytic enzyme human plasmin, characterized in part by its ability to hydrolyze lysine and arginine esters and protein substrates su...

Journal: :Thrombosis and Haemostasis 2014

Journal: :Journal of the American College of Cardiology 2002

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