The aquatic environments play a critical function in the widespread of antibiotic-resistant bacteria, ultimately impacting human health. We evaluated abundance Enterobacteriaceae and various resistance gene determinants final effluents wastewater treatment plants (WWTPs) Eastern Cape Province, Republic South Africa. A total 44 presumptive was recovered following standard isolation methods. Upon...

Four nontyphoidal Salmonella strains with resistance to extended-spectrum cephalosporins and nonclassical quinolone resistance phenotype were studied. Two S. Give were isolated from pediatric patients with acute gastroenteritis, and two S. Heidelberg were recovered from raw chicken meat. Phenotypic characterization included antimicrobial susceptibility testing and detection of extended-spectrum...

Extended-spectrum cephalosporin-resistant (ESCR) Enterobacteriaceae pose a serious infection control challenge for public health. The emergence of the ESCR phenotype is mostly facilitated by plasmid-mediated horizontal extended-spectrum β-lactamases (ESBLs) and AmpC gene transfer within Enterobacteriaceae. Current data regarding the plasmid contribution to this emergence within the Dutch human ...

A transferable plasmid encoding SHV-12 extended-spectrum beta-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and Acinetobacter baumannii bacteria. A similar plasmid was present among isolates of four different bacterial species. Recognition of plasmid transfer is crucial for control of outbreaks of multidrug-resistan...

The emergence of resistance to extended-spectrum cephalosporins in salmonellae is an increasing clinical problem. We report the characteristics of a ceftriaxone-resistant Salmonella enterica serovar Hadar strain collected in 2001 from a patient with a postoperative wound infection in a university hospital in Taiwan. Resistance to extended-spectrum cephalosporins was found to be due to productio...

objective(s) extended-spectrum beta-lactamase (esbl) producing bacteria have an important role in nosocomial infections. due to the limited availability of information about the molecular epidemiology of esbl producing bacteria in mashhad, we decided to investigate about tem, ctx and shv esbls among urinary escherichia coli isolates in mashhad, a city in northeast iran. materials and methods   ...

BACKGROUND The Salmonella genomic island 1 (SGI1) is a Salmonella enterica-derived integrative mobilizable element (IME) containing various complex multiple resistance integrons identified in several S. enterica serovars and in Proteus mirabilis. Previous studies have shown that SGI1 transfers horizontally by in trans mobilization in the presence of the IncA/C conjugative helper plasmid pR55. ...

background clinical significance of extended-spectrum beta-lactamases (esbls) production in enterobacter spp. has not well been established. objectives this study was conducted to investigate the prevalence of esbls produced by enterobacter spp. in clinical isolates. materials and methods this descriptive cross-sectional study was performed during may 2010 to april 2012 in the city of sanandaj,...

introduction: extended spectrum beta-lactamase (esbl) producing escherichia coli generate a major problem for clinical therapeutics and epidemiological study. the incidence of esbl producing strains among clinical isolates has been steadily increasing during the past few years, and remains an important cause of failure of therapy with cephalosporins. the aim of this study was to determine the a...

Multidrug resistant (MDR) Klebsiella pneumoniae is a common cause of nosocomial infections worldwide. Recent years have seen an explosion of resistance to extended-spectrum β-lactamases (ESBLs) and emergence of carbapenem resistance. Here, we examine 198 invasive K. pneumoniae isolates collected from over a decade in Kilifi County Hospital (KCH) in Kenya. We observe a significant increase in MD...