We report a case of Epstein-Barr virus (EBV)-positive ileal extraosseous plasmacytoma containing plasmablastic lymphoma components with CD20-positive lymph node involvement. A 34-year-old healthy Japanese male developed intussusception due to an ileal plasmacytoma. The lesion was positive for EBV-encoded small nuclear RNA in in situ hybridization, with the surrounding lymph nodes showing the ex...

BACKGROUND AND OBJECTIVES Plasmacytoma is a systemic malignancy and it is the most frequent primary tumor affecting the skeleton. Progression from solitary plasmacytoma to systemic diffusion is reported to be 65-100% in 15 years. A case report of a rare 22-year follow-up of a thoracic solitary plasmacytoma is here presented. MATERIAL AND METHODS Clinical case analysis, radiographs, magnetic r...

Extramedullary plasmocytoma occurs in the nasal cavity relatively rarely. Basing upon the case of a 59-year old woman, the authors discuss the difficulties of diagnostic treatment and the course of the disease.

The authors present a rare case of plasmacytoma of the orbit involving lacrimal gland with secondary transformation into multiple myeloma in a 42-year-old woman. The lesion was surgically removed and analyzed. Histopathological examination with immunostaining revealed it to be positive for immunoglobulin G and Kappa chains, demonstrating monoclonality. However, no abnormality was observed on se...

We report on 205 patients with haematologic neoplasms of bone treated from 1985 to 2009. There were 77 patients with primary bone lymphoma, 77 with myeloma and 51 with plasmacytoma. All patients had medical treatments; 43 patients had wide and 162 intralesional surgery. Mean follow-up was 5 years (median, 3.5 years); 11 patients were lost to followup. At the latest examination, 99 patients were...

BACKGROUND Extramedullary plasmacytomas are seldom solitary and usually progress to diffuse myelomatosis. Plasmacytomas of the breast are rare, especially when not associated multiple myeloma. Synchronous infiltrating ductal carcinoma and primary extramedullary plasmacytoma of the breast have not previously reported. CASE PRESENTATION A 27-years-old woman with an untreated upper outer quadran...

We describe herein an extramedullary plasmacytoma (EMP) in the retroperitoneal space, an uncommon manifestation of plasma cell tumor occurred in a rare site. Only a few cases have been reported in a search of English-language literature. In this report, the imaging appearances of the tumor in both computed tomography (CT) and sonography will be presented. With relevant laboratory data and histo...

Indomethacin given continuously in the drinking water (20 micrograms/ml) to BALB/cAn pi mice during the latent period of pristane-induced plasmacytoma development dramatically reduced the plasmacytoma incidence from 34.9 to 2.2%. Additionally, indomethacin given from day 0 to 120 or begun as late as 60 d after a single injection of 1.0 ml pristane was also highly effective in reducing the devel...

BACKGROUND Plasma cell neoplasms represent autonomous proliferations of plasma cells and can manifest as diffuse myeloma with systemic involvement (plasma cell myeloma or multiple myeloma), monoclonal gammopathy of undetermined significance (MGUS), or as variants of plasma cell myeloma such as indolent myeloma, smoldering myeloma, osteosclerotic myeloma, plasma cell leukaemia and non-secretory ...

introduction plasma cell dyscrasias are characterized by a monoclonal neoplastic proliferation of plasma cells. solitary bone plasmacytoma (sbp) is a local form of the disease with the vertebrae and long bones being the most frequently encountered sites. its prevalence in the maxillofacial area is extremely rare. case presentation a 70-year-old caucasian male patient was referred for the extrac...