Adjustment of phenytoin dosage in patients is very difficult due to its nonlinear metabolism and patient to patient variation in its kinetics. It has been recommended that the dosage of phenytoin should be adjusted according to its plasma concentration and requirements of the patients. Therefore, the present study was carried out to identify the various factors which may influence the plas...

OBJECTIVES Maternal death from hemorrhage in low resource settings is frequently due to long delays in transportation to referral centers and/or in obtaining blood and surgical interventions. This case series was designed to demonstrate the feasibility, efficacy and safety of the non-inflatable anti-shock garment (NI-ASG) for resuscitation and hemostasis in the initial management of obstetric h...

intradermal injection of autologous serum and plasma elicit a cutaneous reactivity in almost 45-60% of patients with chronic idiopathic urticaria (ciu).   this reactivity is associated with the presence of auto antibodies against ige or ige receptors. this study was carried out to compare the cutaneous reactivity of autologous serum and plasma skin tests in a series of patients with ciu for dia...

BACKGROUND Adult critically ill patients often suffer from acute circulatory failure, necessitating use of vasopressor therapy. The aim of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) task force for Acute Circulatory Failure was to present clinically relevant, evidence-based treatment recommendations on this topic. METHODS This guideline was developed accordi...

BACKGROUND Splenic artery aneurysms (SAA) are uncommon but the most common visceral artery aneurysm. Splenic artery aneurysms are important to recognize because up to 25% may be complicated by rupture and the mortality rate after rupture is between 25% and 70%. CASE REPORT We present a patient who have abdominal pain. Previously healthy 22-year-old female admitted to emergency department with...

accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. to evaluate the association of oxidized low- density lipoprotein (ox-ldl) with the development of diabetic nephropathy, plasma level of ox-ldl were measured in 70 diabetic patients with macro and 63...

Poor condition subarachnoid hemorrhage (SAH) patients present a high mortality and morbidity. In this study, we reviewed the acute interventional (surgical and endovascular) management of 109 SAH-poor condition patients, who were treated as early as logistically possible after confirming stable circulation parameters. Patients over the age of 70 years, without clinical response to painful stimu...

Circumcision has been the most frequently applied surgical procedure since ancient times [1,2]. In Turkey, the application of this surgical procedure continues due to traditional and religious reasons. Iron deficiency anemia (IDA) is a common pediatric problem affecting up to 25% of all the children worldwide [3].Even though circumcision is known to be a procedure with minor complications, it c...

INTRODUCTION — This topic will review the physiologic determinants and classification of shock. The initial evaluation and management of shock in children, in general, and hypovolemic and septic shock, specifically, are discussed separately. (See "Initial evaluation of shock in children" and "Initial management of shock in children" and "Hypovolemic shock in children: Initial evaluation and man...