We examined the effects of the dietary intake of medium- and long-chain triacylglycerol (MLCT) on hyperglycemia in diabetic ob/ob mice. Six-week-old male ob/ob mice were fed a diet containing longchain triacylglycerol (LCT) or MLCT for 3 wks. During the dietary treatment, we determined the plasma glucose and insulin concentrations in the fed state once a week. Whereas the body weights did not d...

The effects of 1) a rapid intravenous injection of insulin (4.4 IU), 2) a continuous intravenous infusion of insulin (.14 IU/min), or 3) a rapid intravenous injection of glucose (.24 g/kg body weight) into nonpregnant ewes and 4) a continuous intravenous infusion of glucose (1.2 mg/kg body weight/rain) into pregnant ewes on plasma amino acid metabolism and a-amino acid nitrogen (~-NH 2 -N) upta...

In the current study, we determined whether increased digestion of starch by high salivary amylase concentrations predicted postprandial blood glucose following starch ingestion. Healthy, nonobese individuals were prescreened for salivary amylase activity and classified as high (HA) or low amylase (LA) if their activity levels per minute fell 1 SD higher or lower than the group mean, respective...

Abtract Introduction: Visfatin is a newly discovered adipokine which is highly expressed in visceral adipose tissue that may induces changes in insulin resistance. The Aim of this study was to examine the Effect of Endurance Exercise on Visfatin and Insulin Levels In Obese Women. Method: present research is a semi-empirical study that 10 obese female volunteers (age 35.6±7.12 y, body mass in...

of delivery (14) the mean (±SE) plasma concentration of glucose was 99±7 mg/100 ml, insulin 32±6 ,uU/ml, glucagon 183±17 pg/ml. These levels were similar to those occurring in mothers who did not have an i.v. infusion, permitting pooling of the two groups for further analysis. The 't' test for paired data was used for statistical comparison of plasma concentrations of metabolite or hormones. Th...

Insulin resistance and obesity are both associated with lower plasma adiponectin concentrations. Since insulin resistance and obesity are related, the extent to which the association of adiponectin with insulin resistance is dependent on its relationship with obesity is unclear. To address this issue, fasting plasma adiponectin concentrations were measured in 60 nondiabetic subjects, stratified...

PURPOSE To investigate the influence of low dose clonidine premedication on perioperative glucose homeostasis. METHODS Sixteen patients undergoing abdominal hysterectomy for benign uterine myoma were randomly assigned to receive either iv clonidine (1 microg x kg(-1)) 30 min before induction of general anesthesia (clonidine, n=8) or saline (control, n=8). Plasma concentrations of glucose, ins...

The effects of halothane anaesthesia on glucose metabolism have been investigated in rats after a non-lethal scald injury. Anaesthesia was induced about 70 min after injury. Glucose metabolism was studied at two stages: during and shortly after induction, and about 2 h after induction. Comparisons were made with conscious rats at the corresponding times after injury. All rats were in an ambient...

Postprandial cellular glucose uptake is dependent on an insulin-signaling cascade in muscle and adipose tissue, resulting in the translocation of the insulin-dependent glucose transporter 4 (Glut4) into the plasma membrane. Additionally, extended food deprivation is characterized by suppressed insulin signaling and decreased Glut4 expression. Northern elephant seals are adapted to prolonged fas...