tobacco smoke contains numerous compounds, many ‎of which are oxidants and capable of producing free radical and enhancing ‎the oxidative stress. the aim of this study was to investigate the effect of cigarette smoking on the erythrocyte antioxidative enzyme activities and the plasma ‎concentration of their cofactors. ‎sixty eight healthy men were enrolled, 32 of whom had never smoked and 36 ha...

Background: Prostate specific antigen (PSA) has been used as a screening test for the early detection of prostate cancer (PC) for many years. Although the introduction of PSA test led to a considerable increase in reported prostate cancer cases, there is still some controversy over the sensitivity and specificity of this marker in distinguishing PC patients from those with benign prostate hyper...

Ghrelin increases food intakes and body weight. Bombesin decreases food intakes and inhibits the stimulatory effect of Ghrelin on food intakes. Thyroid hormones have a crucial role in the regulation of body weight and yet the effect of bombesin on thyroid axis activity is not fully clear. Therefore, the goal of this study was to determine the effect of different doses of Ghrelin or bombesin on ...

to estimate the effect of microencapsulated fish oil on blood metabolites, rumen and blood plasma fatty acids concentrations twelve sannan dairy goats with 30 ± 5 days in milk (dim) were allocated to 3 treatments in a 3×2 change over design with 2 periods of 30 days. treatments were: 1) the control (without fish oil), 2) microencapsulated fish oil (2% fish oil capsulated in 6% treated whey prot...

the objective of this study was to evaluate kinetics and the residual decline of tylosin in milk and plasma of lactating najdi ewes following single intramuscular injection of tylosin at the dose of 10 mg/kg. blood and milk samples were collected from the ewes before and at different time intervals after treatment. tylosin concentrations were determined by microbiological agar plate assay using...

background: in this study we have prepared the iga solution from normal human plasma using plasma fractionation and ion exchange chromatography. materials and methods: using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction iii was prepared as a suitable source for iga preparation. then it was treated with caprylic acid for separation of impurities. for enrichment o...

objective: cigarette is a rich source of oxidants and reactive nitrogen species. nitric oxide (no) in high concentration has deleterious effects on human sperm function. antioxidant defense system in seminal plasma protects spermatozoa from the attack of reactive oxygen metabolites. the purpose of this study was to determine the correlation between cigarette smoking with the no levels and the t...

in this study, the pharmacokinetic parameters of two marketed tablet formulations of ketoconazole were studied, and the relative bioavailability of the test formulation was compared with a reference formulation. a single dose (12x2) double blind randomized cross-over study of a generic formulation of ketoconazole tablet (2x200 mg), and a commercial brand, nizoral tablet (2x200 mg, janssen pharm...

evidence supports the involvement of nitric oxide (no) in a varity of male reproductive processes such as spermatogenesis, spermiogenesis, sperm motion, sperm metabolism and sperm capacitation. however, low concentration of no is essential in biology and physiology of spermatozoa, but high amounts of no is toxic and has negative effects on sperm functions. on the other hand, it is established t...