The total ionizing dose sensitivity of planar 150 nm CMOS technology is evaluated by measuring the DC responses nMOSFETs at several irradiation steps up to 125 krad(SiO2). Different TID sensitivities are measured for transistors built with different channel dimensions and operating voltages (I/O core). experimental results evidence strong relations between doping profiles in channel. I/O have h...

The application of electrical fields within a microfluidic channel enables many forms of manipulation necessary for lab-on-a-chip devices. Patterning electrodes inside the microfluidic channel generally requires multi-step optical lithography. Here, we utilize an ion-implantation process to pattern 3D electrodes within a fluidic channel made of polydimethylsiloxane (PDMS). Electrode structuring...

Sarcoplasmic reticulum (SR) contains a Ca2+-conducting channel that is believed to play a central role in excitation-contraction coupling by releasing the Ca2+ necessary for muscle contraction. The effects of calmodulin on single cardiac and skeletal muscle SR Ca2+-release channels were studied using the planar lipid bilayer-vesicle fusion technique. Calmodulin inhibited Ca2+-release channel op...

Keyhole limpet hemocyanin forms ion-conducting channels in planar lipid bilayer membranes. Ionic current through the open hemocyanin channel presents the following characteristics: (a) it is carried mainly by cations; (b) it is a nonlinear function of membrane potential; (c) channel conductance is a saturating function of ion activity; (d) it shows ionic competition. A model for the open hemocy...

In this review article, basic properties of NAND flashmemory cell strings which consist of cells with virtual source/drain (S/D) (or without S/D) were discussed. The virtual S/D concept has advantages of better scalability, less cell fluctuation due to effectively longer channel length at the same technology node, and less program disturbance. The fringing electric field from the control-gate a...

Mitochondrial calcium uniporter (MCU) channel is responsible for Ruthenium Red-sensitive mitochondrial calcium uptake. Here, we demonstrate MCU oligomerization by immunoprecipitation and Förster resonance energy transfer (FRET) and characterize a novel protein (MCUb) with two predicted transmembrane domains, 50% sequence similarity and a different expression profile from MCU. Based on computati...

Multi-terminal artificial synaptic devices are promising for building neural morphological networks and manufacturing chips. In this study, planar multi-gate InOx-based transistor was demonstrated by using solution-processed AlOx as an electric double layer (EDL) dielectric with mobile hydrogen protons. The excitatory postsynaptic current (EPSC) successfully controlled adjusting amplitude, dura...

Pseudomonas aeruginosa OprD is a specific porin which facilitates the uptake of basic amino acids and imipenem across the outer membrane. In this study, we examined the effects of deletions in six of the proposed eight surface loops of OprD on the in vivo and in vitro functions of this protein. Native OprD formed very small channels in planar lipid bilayers, with an average single-channel condu...

A quantization theorem for the edge currents is proven for discrete magnetic half-plane operators. Hence the edge channel number is a valid concept also in presence of a disordered potential. Under a gap condition on the corresponding planar model, this quantum number is shown to be equal to the quantized Hall conductivity as given by the Kubo-Chern formula. For the proof of this equality, we c...