Pituitary adenomas are common benign tumors that may or may not produce hormones that are rarely malignant. Those that do not generate hormones are considered non-functioning or non-secretory. Non-secretory pituitary adenomas are defined as tumors of the pituitary gland that lack the characteristic of hormone hypersecretion and account for 18 to31% of all surgically treated pituitary adenomas [...

Tumors of the pituitary make up approximately 7 per cent of the intracranial neoplasms of man (61). As isolated cases they have been found in the horse (41, 48), dog (29, 37), cow (1), deer (53), Indian buffalo (16), baboon (25), and mouse (@3, 54). Following the description by Olga Fischer of large hypophyseal adenomas in two old rats (15), several investigators have reported a high mci dence ...

Pituitary adenomas are neoplasms of the anterior pituitary lobe and account for 15-20% of all intracranial tumors. Although most pituitary tumors are benign they can cause severe symptoms related to tumor size as well as hypopituitarism and/or hypersecretion of one or more pituitary hormones. Most pituitary adenomas are sporadic, but it has been estimated that 5% of patients have a familial bac...

Pituitary adenomas (PA) constitute about 10% of intracranial neoplasm. Most of them have its origin in adenohypophysis (Cury et al., 2009; Rosai, 1989). They occur most often in adults between the ages of 30 and 60 years, and may have slightly higher incidence in females in early life (20-45 years) and in males in later life (35-60 years) (Davis et al., 2001; McDowell et al., 2011). The majorit...

Pituitary tumors are rare in childhood and adolescence, with a reported prevalence of up to 1 per million children. Although pituitary tumors are rare in childhood and adolescence, and are typically histologically benign, significant morbidity may result due to their location, mass effect, and/or interference with normal pituitary hormone functions. The frequency of macro adenomas and aggressiv...

The proportion of elderly subjects is growing in Western countries and, as a consequence, several diseases are now recognized with increasing frequency in the older segment of the population. Pituitary tumors are no exception to the rule. However, the presentation, diagnosis and management of pituitary tumors in the elderly, defined as patients older than 65 or 70 years depending on the differe...

BACKGROUND The aim of the study is to analyze the nature, extensions, and dural relationships of hormonally inactive giant pituitary tumors. The relevance of the anatomic relationships to surgery is analyzed. METHODS There were 118 cases of hormonally inactive pituitary tumors analyzed with the maximum dimension of more than 4 cm. These cases were surgically treated in our neurosurgical depar...

Epigenetically-mediated gene dysregulation is a common feature associated with human pituitary tumorigenesis. The mechanisms leading to these changes, however, remain largely unknown. In this review, we examine changes responsible for DNA and histone modifications as independent, butpotentially interrlated modes of communication effecting chromatin remodeling. The dynamic properties of the enzy...

www.PituitaryCongress2003.com The Pituitary Society Officers & Board of Directors President 2002-2003 Shlomo Melmed, Los Angeles, CA, USA President Elect 2003-2004 David Clemmons, Chapel Hill, NC, USA Executive Director Mary Lee Vance, Charlottesville, VA, USA Secretary-Treasurer David L Kleinberg, New York, NY, USA Board of Directors Felipe Casanueva, Santiago de Compostela, Spain David Clemmo...