Prophet of Pit-1 (Prop1) is a transcription factor that regulates Pit-1 gene expression. Because Pit-1 regulates the differentiation of pituitary cells and the expressions of GH, prolactin and TSHbeta genes, Prop1 mutation results in combined pituitary hormone deficiency in humans. However, Prop1-binding sites in human Pit-1 gene and the mechanism leading to combined pituitary hormone deficienc...

Shelter staff and veterinarians routinely make subjective dog breed identification based on appearance, but their accuracy regarding pit bull-type breeds is unknown. The purpose of this study was to measure agreement among shelter staff in assigning pit bull-type breed designations to shelter dogs and to compare breed assignments with DNA breed signatures. In this prospective cross-sectional st...

Tests of Pavlovian-instrumental transfer (PIT) demonstrate that reward-predictive stimuli can exert a powerful motivational influence on the performance of instrumental actions. Recent evidence suggests that predictive stimuli produce this effect through either the general arousal (general PIT) or the specific predictions (outcome-specific PIT) produced by their association with reward. In two ...

This study offers initial research on Physically Interactive Technology (PIT). Findings of this research reveal how people made sense of PIT, how the ways people understand PIT reveal presence due to physical interaction, and how PIT challenges the definition of online interaction. Current and past literature on social presence theory and social cues theory provide a rationale for how “present”...

Strong acid mine drainage (AMD) processes in the flooded, formerly open pits Lusatia area present an enormous environmental challenge for rehabilitation of post-mining landscape. Extensive and costly monitoring is required optimal AMD management remediation planning control. Because large size dimension problem, regular sampling can only provide limited point data, which needs to be extrapolate...

In this paper, we construct the q-Schur modules as left principle ideals of the cyclotomic q-Schur algebras, and prove that they are isomorphic to those cell modules defined in [3] and [10] at any level r. Then we prove that these q-Schur modules are free modules and construct their bases. This result gives us new versions of several results about the standard basis and the branching theorem. W...

A 37-year-old man presented with an optic nerve pit and serous macular detachment of the left eye. Scanning laser ophthalmoscopy revealed a cyst-like structure terminating at the pit in the premacular vitreous. During ocular movement, this structure moved vigorously and seemed to exert traction on the pit. We believe that it is part of an anomalous Cloquet's canal, and that traction on the pit ...

Experiments about single pit initiation and propagation were performed on 316L stainless steel with the aim to determine the pitting corrosion behaviour for nuclear waste containers. The experimental setup permits to control the pit development at will and to create reproducible single pits in three dimensions. Radial and deep evolutions of a disc shaped pit were studied for propagation times o...

INTRODUCTION We present a case of a man with optic disc pit maculopathy, whose vision improved after vitrectomy combined with glial tissue removal from the optic pit area, and without the use of photocoagulation. CASE PRESENTATION A 45-year-old man complained of blurred vision, and ophthalmoscopy revealed a retinal detachment and retinoschisis extending from an optic disc pit through the macu...

BACKGROUND The transcription factor pituitary-1 (Pit-1) is mainly expressed in the pituitary gland, where it has critical roles in cell differentiation and as a transcriptional factor for GH and prolactin (PRL). It is also expressed in human extrapituitary tissues (placenta, lymphoid and haematopoietic tissues) and cell lines (human breast adenocarcinoma cells, MCF-7). Despite the widely sugges...