Winkler's disease otherwise known as chondrodermatitis nodularis chronica helices (CNHC) is characterized by a painful persistent erythematous nodule, mostly located at the rim of helix of pinna. Occurs mostly in men over 40 years of age. Standard therapy is by local excision or carbon dioxide laser vaporization. Recurrence is frequent.

Life-threatening hyperthermia occurs in some individuals taking 3,4-methylenedioxymethamphetamine (MDMA, ecstasy). In rabbits, sympathetically mediated vasoconstriction in heat-exchanging cutaneous beds (ear pinnae) contributes to MDMA-elicited hyperthermia. We investigated whether MDMA-elicited cutaneous vasoconstriction and hyperthermia are reversed by clozapine and olanzapine, atypical antip...

The self-memory relationship is thought to be bidirectional, in such a way that memories provide context for the self, and equally, the self exercises control over retrieval (Conway, 2005). Autobiographical memories are not distributed equally across the life span; instead, memories peak between ages 10 and 30. This reminiscence bump has been suggested to support the emergence of a stable and e...

The human external ears, or pinnae, have an intriguing shape and, like most parts of the human external body, bilateral symmetry is observed between left and right. It is a well-known part of our auditory sensory system and mediates the spatial localization of incoming sounds in 3D from monaural cues due to its shape-specific filtering as well as binaural cues due to the paired bilateral locati...

701 PREVIOUS STUDIES FROM THIS LABORATORY HAVE BROUGHT FORTH EVIDENCE SUGGESTING THAT IMBALANCES BETWEEN CAROTID AND VERTEBRAL blood flow and temperature underlie the increase in preoptichypothalamic temperature during rapid eye movement (REM) sleep in several mammalian species.1 Particularly relevant to the mechanism of such a temperature increase are the effects on preoptic-hypothalamic tempe...