Diabetes mellitus is a complex multifarious metabolic disorder characterized by chronic hyperglycemia that requires non-stop treatment with multiple factors will reduce the risk of long-term complications and drug side effects. Streptozotocin well known for its selective pancreatic islet β-cell cytotoxicity used to induce diabetes in animals. It also interferes cellular oxidative mechanisms. Ph...

Cassia siamea is widely used in Thailand as an anxiolytic drug. A case of a middle-aged non-alcoholic female patient who presented to the physician with the abnormal elevation transaminase enzyme is reported in this paper. She was investigated for hepatitis profile and negative serological result. She revealed the use of the traditional herb capsule of Cassia siamea. Her liver function returned...

Plants are the primary source of medicine for most of the world. The most fundamental step in the scientific study of medicinal plants is establishing their botanical identity. Many studies lack voucher specimens, which serve as permanent records of scientific investigations. This omission makes positive identification impossible and hinders reproducibility. Even when vouchers are cited, scient...

This study investigated the therapeutic effects of Vernonia amygdalina aqueous leaf extract administration on Salmonella typhimurium infected Wistar rats. Rats were orally by a single dose (1.5 x 108 CFU). Negative control groups and treated with vehicle (distilled water), neutral group not infected, while four test up to 24 days 50 mg/kg. 100 mg/kg, 150 mg/kg 200 body weight V. respectively. T...

The purpose of this study was to determine the hypoglycaemic effects leaf and bark extracts Bauhinia rufescens Lam, used in traditional medicine for diabetes Senegal. Phytochemical screening hydromethanolic hydro-acetonic obtained from leaves barks carried out according standard analytical methods. Experiments were on normoglycemic diabetic mice. These after injection a single dose glucose (4 g...

Objective: To evaluate the effect of NIPRD-AM1 on CYP3A4 in order to generate clinically significant data for its safe and efficacious use. Materials and Methods: NIPRD-AM1 is a phytomedicine developed from aqueous root extracts of Nauclea latifolia Smith (Rubiaceae) for the treatment of uncomplicated malaria. The effect of NIPRD-AM1 on CYP3A4 was measured with and without the addition of NIPRD...