Context Lifestyle modifi cation is the cornerstone of treatment in type 2 diabetes. Improved nutrition or increased physical activity both improve glycaemic control,1 2 but whether diet and exercise have a synergistic effect is not established. This study examined whether an intensive dietary intervention plus physical activity advice had additional benefi ts compared with an intensive dietary ...

BACKGROUND Dietary factors have been discussed to influence risk or disease course of multiple sclerosis (MS). Specific diets are widely used among patients with MS. OBJECTIVE To design and pilot-test an evidence based patient education program on dietary factors in MS. METHODS We performed a systematic literature search on the effectiveness of dietary interventions in MS. A web-based surve...

Eukaryotic genomes are packaged into chromatin by histone proteins whose chemical modification can profoundly influence gene expression. The histone modifications often act in combinations, which exert different effects on gene expression. Although a number of experimental techniques and data analysis methods have been developed to study histone modifications, it is still very difficult to iden...

Epidemiological studies on the prevalence of musculoskeletal pain have consistently shown that this is a relevant health problem, with non-specific low back pain (LBP) being the most commonly reported in adult females. Conflicting data on the association between LBP symptoms and physical activity (PA) have been reported. Here, we investigated the prevalence of LBP and the effect of a 24-month n...

The potential to genetically modify human germlines has reached a critical tipping point with recent applications of CRISPR-Cas9. Even as researchers, clinicians, and ethicists weigh the scientific and ethical repercussions of these advances, we know virtually nothing about public attitudes on the topic. Understanding such attitudes will be critical to determining the degree of broad support th...

Postsynthetic modification of metal-organic frameworks (MOFs) has proven a hugely powerful tool to tune physical properties and introduce functionality, by exploiting reactive sites on both the MOF linkers their...

This article is a literature review related to the methods of functionalization carbon fibers for tissue engineering applications. Through physical modification, it possible obtain layer chemical compound on surface and impart additional properties. On other hand, modification may lead incorporation appropriate functional groups into fiber structure, capable attaching, among others, biologicall...

curcumin is a natural polyphenolic compound with anti-cancer, anti-inflammatory, and anti-oxidation properties. low water solubility and rapid hydrolytic degradation are two challenges limiting use of curcumin as therapeutic agent. in the current study, the role of the native/modified forms of bovine serum albumin (bsa) and casein, as food-grade biopolymers and safe drug delivery systems, on th...

ISSUE ADDRESSED Community-based lifestyle modification programs can be a valuable strategy to reduce risk factors for chronic disease. However, few government-funded programs report their results in the peer-reviewed literature. Our aim was to report on the effectiveness of the Healthy Eating Activity and Lifestyle (HEAL) program, a program funded under the Australian government's Healthy Commu...