Novel derivatives of the apple-derived flavonoid phloridzin have been found to be potent antioxidants in vitro [I] . The antioxidant action of oestrogens such as 17 P-oestradiol may contribute to their cardioprotective effects [2]. Phloretin the aglycone form of phloridzin has been reported to be oestrogenic [3] and its 3-hydroxy derivative may have enhanced weak oestrogen activity that could e...
