Dr. Neumann recently assumed the position of Global Head of Knowledge Management at Aventis Pharmaceuticals. the U.S. pharmaceuticals business of Aventis, a world leader in pharmaceuticals and human vaccines. Prior to that he was Vice President, Strategic Informatics and Head of Knowledge Research at Beyond Genomics, a privately owned life sciences research company founded in the fall of 2000 a...

In the previous years the synthesis of high nitrogen containing heterocyclic systems has been attracted to many pharmaceutical and agrochemical industries. The triazole nucleus is one of the most important heterocycles which is a feature of natural products and medicinal agents. Triazole nucleus is enjoying their importance as being the center of activity. The nitrogen containing heterocyclics ...

The authors are responsible for the veracity of the facts stated and the views and opinions expressed in this report. Responsibility for these should not be attributed to the MIT-Zaragoza International Logistics Program, the Zaragoza Logistics Center, DFID or the policy directors and funders of these research institutes.

Genotoxic compounds induce genetic mutations and/or chromosomal rearrangements and can therefore act as carcinogenic compounds (McGovern and Jacobson-Kram, 2006). These compounds cause damage to DNA by different mechanisms such as alkylation or other interactions that can lead to mutation of the genetic codes. In general, chemists employ the terms "genotoxic" and "mutagenic" synonymously; howev...

Recently the concerns about environmental contaminants has widened to include not just persistent organic pollutants like pesticides (POPs) but pharmaceuticals and personal care products (PPCPs) as well. PPCPs encompass a broad class of chemicals, ranging from over-the-counter and prescription drugs, to sunscreen and fragrances. Unlike priority pollutants, most PPCPs are not lipophilic, so they...

© 2016 Joule Inc. or its licensors CMAJ 1 Competing interests: Mandar Jog reports honoraria from Merz Pharmaceuticals, Allergan and AbbVie; and grants from the Canadian Institutes of Health Research, Academic Medical Organization of Southwestern Ontario, Lawson Health Research Institute, AGE-WELL Networks of Centres of Excellence, Merz Pharmaceuticals and Boston Scientific. He occasionally serv...

The worldwide heavy use of veterinary pharmaceuticals in confined animal-feeding operations has resulted in annual discharge of 3,000–27,000 tons of drug chemicals via livestock manure into the environment. More than 50 major antibiotics have been detected in poultry, swine, cattle, and horse manures at 0.01–765 mg kg 1 dry manure mass. In animal manures, most veterinary pharmaceuticals degrade...