After the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. Such biota as the tropical forest, a quantity of plants credi...

A system using energy-dispersive X-ray diffraction (EDXRD) has been developed and tested using multivariate calibration for the quantitative analysis of tablet-form mixtures of common pharmaceutical ingredients. A principal advantage of EDXRD over the more traditional and common angular dispersive X-ray diffraction technique (ADXRD) is the potential of EDXRD to analyse tablets within their pack...

Recent anecdotal evidence suggests that it is becoming increasingly popular among ecstasy users to attempt to negate certain side-effects or enhance the drug experience through the concomitant use of pharmaceutical drugs or supplements. This study was designed to explore the practice of deliberately using pharmaceuticals for any reason in association with ecstasy and related drug (ERD) use. A c...

Recombinant DNA technology and corresponding innovations in molecular biology, chemistry and medicine have led to novel therapeutic biomacromolecules as lead candidates in the pharmaceutical drug development pipelines. While monoclonal antibodies and other proteins provide therapeutic potential beyond the possibilities of small molecule drugs, the concomitant demand for supportive bioanalytical...

Mass spectrometry imaging (MSI) is a mass spectrometry based molecular ion imaging technique. It provides the means for ascertaining the spatial distribution of a large variety of analytes directly on tissue sample surfaces without any labeling or staining agents. These advantages make it an attractive molecular histology tool in medical, pharmaceutical, and biological research. Likewise, MSI h...

p-Chloro-m-cresol(PCMC) is widely used in pharmaceutical industries as biocide and preservative. However, it faces the problems of solubility in water and photo degradation. The aim of present study was to evaluate the impact of biofield treatment on physical, thermal and spectral properties of PCMC. For this study, PCMC sample was divided into two groups i.e., one served as treated and other a...

Hyperspectral imaging – or spectral imaging – was first used in the material, food and biological domains. But it is increasingly being employed by pharmaceutical professionals, since it combines the dual advantages of spectroscopic techniques and imaging. Hyperspectral imaging allows the user to acquire the spectrum at each pixel of a defined image. It is thus possible to visualise properties ...

a simple and sensitive high performance liquid chromatographic method with electrochemical detection is described for the quantitative determination of the amoxycillin and clavulanic acid in pharmaceutical dosage forms. separation of sample components occurs on a reversed phase c18 column with a mobile phase consisting of methanol-water-phosphate buffer. for the amperometric detection, the pote...

Article can be accessed online on: www.ijpsr.com ABSTRACT: The determination of drugs in pharmaceutical preparations and biological fluids is of pivotal importance in the pharmaceutical and medical sciences. Successful analysis requires sensitivities at ppb level or even less in biological fluids with high selectivity and minimal interferences from various artifacts. Till recently, biopharmaceu...

Pharmaceutical industry is currently undergoing a transient phase with new orientation. Loss of financial resources, presence of new therapeutic agents and increasing cost of research and development have called for a full.scale restructuring within the pharmaceutical industry to retain even the most basic competitiveness. The development of new technologies has been as one way out of the dile...