نتایج جستجو برای: phagocytic index

تعداد نتایج: 403411  

Journal: :Physiological research 2003
E Matalová A Spanová F Kovárů

The effect of phagocytosis of living bacteria on apoptotic DNA changes was examined in pig leukocytes in relation to immune system maturation. Blood samples of pigs (aged 6, 12 and 18 weeks) were cultivated with a suspension of bacterial cells Salmonella typhimurium LB 5000 at 37 (o)C. In the experimental groups, killed bacteria and microspheric particles were used to detect the influence of th...

Introduction: Trifluralin is a widely-used herbicide that inhibits proper cell proliferation in the root of plants. Therefore, the present study was conducted in order to investigate the effects of trifluralin on immune system of the NMRI mice challenged with sheep red blood cells(SRBCs). Methods: The study population consisted of 14 male NMRI mice randomly catagorized into two equal groups an...

Journal: :Investigative ophthalmology & visual science 1990
T Mano D G Puro

Under a variety of pathologic conditions, glial cells of the retina are capable of phagocytosis. Although phagocytosis may play a role in retinal pathobiology, the regulation of the phagocytic activity of retinal glial cells is poorly understood. We used a culture system to study phagocytosis by human retinal glial cells. The cultured cells were obtained from adult postmortem eyes and were immu...

Journal: :Infection and immunity 1979
L D Loose J Turinsky

The phagocytic and microbicidal activities of alveolar and peritoneal macrophages were evaluated 4 and 24 h after a full-thickness scald burn of 26 to 28% body surface area in anesthetized rats. The contribution of serum factors to the macrophage functions was studied concurrently. The phagocytic activity of alveolar macrophages obtained 4 or 24 postburn was reduced approximately 65% below cont...

Journal: :Vestnik Rossiiskoi akademii meditsinskikh nauk 2014
N S Mynoranskaya P V Sarap E I Mynoranskaya

BACKGROUND Our aim was to identify the mechanisms of immune and cytokine regulation in different clinical forms of Ixodes tick-borne borreliosis. METHODS The clinical observations performed on 581 patients with erythemic (113 patients), non-eritemic (242 patients) forms of Ixodes tick- borne borreliosis and Borrelia co-infection tick-borne encephalitis (226 patients) in the manifestation of t...

2006
Jason E. Holt

We propose Surety Bond PKI, an alternative to high assurance certificates which increases cost disparity between fake and legitimate web sites.

Journal: :Journal of immunology 2011
Kristen E Silver Rene E Harrison

FcγR-mediated phagocytosis is a cellular event that is evolutionary conserved to digest IgG-opsonized pathogens. Pseudopod formation during phagocytosis is a limiting step in managing the uptake of particles, and in this paper, we show that the conventional kinesin is involved in both receptor and membrane delivery to the phagocytic cup. Expression of a mutant kinesin isoform (GFP dominant nega...

Journal: :Current Biology 2021

New work shows that the glycocalyx meshwork on surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components this barrier are present pathogenic malignant targets elude phagocytosis.

2014
Tereza Janotová Marie Jalovecká Marie Auerová Ivana Švecová Pavlína Bruzlová Veronika Maierová Zuzana Kumžáková Štěpánka Čunátová Zuzana Vlčková Veronika Caisová Petra Rozsypalová Katarína Lukáčová Nikol Vácová Markéta Wachtlová Jiří Salát Jaroslava Lieskovská Jan Kopecký Jan Ženka

The application of the phagocytic receptor agonists in cancer immunotherapy was studied. Agonists (laminarin, molecules with terminal mannose, N-Formyl-methioninyl-leucyl-phenylalanine) were firmly anchored to the tumor cell surface. When particular agonists of phagocytic receptors were used together with LPS (Toll-like receptor agonist), high synergy causing tumour shrinkage and a temporary or...

2011
Yong-Han Paik David A. Brenner

NADPH oxidase (NOX) is a multicomponent enzyme complex that generates reactive oxygen species (ROS) in response to a wide range of stimuli. ROS is involved as key secondary messengers in numerous signaling pathways, and NADPH oxidases complex has been increasingly recognized as key elements of intracellular signaling of hepatic fibrogenesis. In the liver, NADPH oxidase is functionally expressed...

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