Nanomedicine is becoming very popular over conventional methods due to the ability to tune physico-chemical properties of nano vectors, which are used for encapsulation of therapeutic and diagnostic agents. However, the success of nanomedicine primarily relies on how specifically and efficiently nanocarriers can target pathological sites to minimize undesirable side effects and enhance therapeu...

the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...

in the present work a ph-dependent cloud point extraction procedure using ph-sensitive hydrogel polymer was applied for preconcentration and spectrophotometric determination of the hg(ii) as its thio micher's ketone complex. central composite design (ccd) and response surface method were applied to design the experiments and find out the optimum conditions. four factors entitled concentration o...

the use of liposome as an adjuvant and a vaccine carrier has been cited previously in the literature. it has also been shown to be effective in enhancing the immunogenicity of vaccine candidates. balb/c mice immunized subcutaneously with outer membrane protein (omp) of brucella abortus s19 vaccine strain entrapped in a commercial cationic liposome (s19-omp-liposome) for vaccine delivery, showed...

Abstract Background Cosmeceuticals are cosmetic products with biologically active components that have drug-like benefits. currently rapidly growing segments encompassing the personal care industry and numerous topical cosmetics-based therapies for treating different skin conditions. The barrier nature of causes limitations to treatment. effectiveness this cosmeceutical product has been enhance...

We studied the cytotoxicity, cellular accumulation, and DNA interac tions induced by liposome-entrapped NDDP (L-NDDP) and cisplatin in A2780 human ovarian carcinoma cells sensitive (A2780/S) and resistant (A2780/PDD) to cisplatin. L-NDDP was 2-fold more cytotoxic than cis platin against A2780/S cells with 5-h or 24-h drug exposure. Both cell lines were equally sensitive to L-NDDP, while A2780/P...

Oxcarbazepine (OXC) was used as first line therapy or additional for treatment of partialand secondary seizures. The penetration OXC into nasal mucosa can be enhanced by formingliposome. This research has the aim to prepare and characterize iposome laoding OXC. OXCliposome formula composed using soya lechitin cholesterol with various amount usingthin film hydration method. Characterization dete...