Mulkey DK, Wenker IC, Kréneisz O. Current ideas on central chemoreception by neurons and glial cells in the retrotrapezoid nucleus. J Appl Physiol 108: 1433–1439, 2010. First published January 21, 2010; doi:10.1152/japplphysiol.01240.2009.—Central chemoreception is the mechanism by which CO2/pH-sensitive neurons (i.e., chemoreceptors) regulate breathing in response to changes in tissue pH. A re...

Central chemoreception is the mechanism by which CO2/pH-sensitive neurons (i.e., chemoreceptors) regulate breathing in response to changes in tissue pH. A region of the brain stem called the retrotrapezoid nucleus (RTN) is thought to be an important site of chemoreception (23), and recent evidence suggests that RTN chemoreception involves two interrelated mechanisms: H+-mediated activation of p...

objective(s) in this study, a kind of ph sensitive composite membrane was prepared and drug permeation through it was investigated in terms of ph. rationale of this study originated from the fact that a ph change which may be a result of a disease state in the body can trigger drug release. materials and methods  here, a kind of ph sensitive composite membrane containing different nanoparticle ...

Objective(s) In this study, a kind of pH sensitive composite membrane was prepared and drug permeation through it was investigated in terms of pH. Rationale of this study originated from the fact that a pH change which may be a result of a disease state in the body can trigger drug release. Materials and Methods  Here, a kind of pH sensitive composite membrane containing different nanoparticle ...

A simple and effective route to design pH-responsive viscoelastic wormlike micelles based on commercial compounds is reported. According to this route, pH-sensitive viscoelastic fluids can be easily obtained by introducing a pH-responsive hydrotrope into a surfactant solution. In this paper, the mixed system of cetyltrimethylammonium bromide (CTAB) and potassium phthalic acid (PPA) was studied ...

This paper focuses on finding criteria to choose the best combination between a pH sensitive material and detection method. Various pH sensitive polymers and measurement methods exist. However, some measurement methods are not sensitive enough to measure pH in the presence of salt and this need to be investigated further. This paper discusses various pH sensitive materials and detection methods...

Central chemoreception is the mechanism by which CO(2)/pH sensors regulate breathing in response to tissue pH changes. There is compelling evidence that pH-sensitive neurons in the retrotrapezoid nucleus (RTN) are important chemoreceptors. Evidence also indicates that CO(2)/H(+)-evoked adenosine 5'-triphosphate (ATP) release in the RTN, from pH-sensitive astrocytes, contributes to chemoreceptio...