BACKGROUND Bisphenol A (BPA) is an applied chemical that is used in many industrial fields and is a potential endocrine disruption chemical (EDC) that is found in the environment. Bisphenol S (BPS) and polyethersulfone (PES) have been suggested as putative BPA alternatives. In this study, the estrogenic potency induced by the binding of 17-beta-estradiol (E2), BPA, BPS, PES and their metabolite...

OBJECTIVE Schizophrenia is associated with atopy and increased inflammatory markers. We report a population-based longitudinal study of the associations between childhood atopic disorders, subsequent serum inflammatory markers, interleukin 6 (IL-6) and C-reactive protein (CRP), and the risk of psychotic experiences (PEs). METHOD PEs were assessed at age 13 years (n=6785). Presence of clinicia...

OBJECTIVE To determine the prevalence, nature and predictors of prescribing errors (PEs) in three mental health hospitals. SETTING Inpatient units in three National Health Service (NHS) mental health hospitals in the North West of England. PARTICIPANTS Trained clinical pharmacists prospectively recorded the number of PEs in newly written or omitted prescription items screened during their r...

BACKGROUND This article reports the 2-year clinical, angiographic, and intravascular ultrasound outcomes of the everolimus-eluting stent (EES) compared with the paclitaxel-eluting stent (PES) in the randomized SPIRIT II trial. METHODS AND RESULTS This was a prospective, single-blind clinical trial in which a total of 300 patients with de novo native coronary artery lesions were randomized to ...

PURPOSE The chemokine receptor CXCR4 was identified as an independent predictor of poor prognosis in primary melanoma. The aim of the study was to investigate the role of CXCR4 in human melanoma metastases. EXPERIMENTAL DESIGN CXCR4 expression was evaluated in melanoma metastases and in metastatic cell lines through immunohistochemistry, immunoblotting, immunofluorescence, and reverse transcr...

Genetically matched pluripotent embryonic stem (ES) cells generated via nuclear transfer or parthenogenesis (pES cells) are a potential source of histocompatible cells and tissues for transplantation. After parthenogenetic activation of murine oocytes and interruption of meiosis I or II, we isolated and genotyped pES cells and characterized those that carried the full complement of major histoc...

An attempt was made to identify nutritional additives that influence the replication of Venezuelan equine encephalomyelitis virus in suspension cultures grown in a defined serum-free medium. Proline, serine, and choline enhanced titers of the virulent PES strain; the progeny population, however, possessed a virulence character that was somewhat different from that of the PES inocula. These nutr...

The recent development in oil and gas industry increases the production and consumption of oil. The enormous amount of oily wastewater produced is urged to be treated to prevent humanity and environment from being threatened. Membrane technology is an appealing alternative for oily wastewater treatment due to its design simplicity, energy efficiency and environmentally benign approach. In this ...