نتایج جستجو برای: permeability flux

تعداد نتایج: 135274  

Journal: :American journal of physiology. Renal physiology 2007
Andrew H J Salmon Ildikó Toma Arnold Sipos P Robert Muston Steven J Harper David O Bates Christopher R Neal János Peti-Peterdi

The glomerular filtration barrier (GFB) is generally considered to consist of three layers: fenestrated glomerular endothelium, glomerular basement membrane, and filtration slits between adjacent podocyte foot processes. Detailed anatomic examination of the GFB has revealed a novel abluminal structure, the subpodocyte space (SPS), identified as the labyrinthine space between the underside of po...

2013
Andrew J. Wells J. S. Wettlaufer Steven A. Orszag

We model buoyancy-driven convection with chimneys – channels of zero solid fraction – in a mushy layer formed during directional solidification of a binary alloy in two dimensions. A large suite of numerical simulations is combined with scaling analysis in order to study the parametric dependence of the flow. Stability boundaries are calculated for states of finite-amplitude convection with chi...

2010
M. A. Saleem Sumanji Bala Liyakat A. Aeajaz

The ability of β-cyclodextrin, hydroxypropyl-β-cyclodextrin, polyvinyl pyrrolidone and urea to influence the percutaneous absorption of meloxicam through isolated rat skin was evaluated. Carrier complex were prepared by kneading method in 1:1 and 1:2 in molar ratios for β-cyclodextrin and hydroxypropyl-β-cyclodextrin and in 1:1, 1:3 and 1:5 in weight ratios for polyvinyl pyrrolidone and urea. T...

Journal: :Anais da Academia Brasileira de Ciencias 2016
Muhammad Ubaid Sadaf Ilyas Sadullah Mir Abida K Khan Rehana Rashid Muhammad Z U Khan Zainab G Kanwal Ahmad Nawaz Amna Shah Ghulam Murtaza

The aim of present study was to enhance topical permeation of clotrimazole gel preparation by using various permeability enhancers such as coconut oil, pistachio oil and sodium lauryl sulphate (SLS). Clotrimazole gel preparations were prepared and optimized by using three factor, five level central composite design. A second-order polynomial equation was generated in order to estimate the effec...

Journal: :Blood 1990
M R Clark M E Rossi

This study investigated the effect of acute deoxygenation on membrane permeability characteristics of sickle cells. Measured fluxes of Na+ and K+ in ouabain-inhibited cells, of chloride and sulfate exchange in 4,4'-diisothiocyanostilbene-2,2'-disulfonate (DIDS)-inhibited and untreated cells, and of erythritol, mannitol, and arabinose in cytochalasin B-inhibited cells indicated that a deoxygenat...

Journal: :The Journal of General Physiology 1965
Ora Kedem Alvin Essig

Precise evaluation of permeability of biological tissues is often prevented by imprecise knowledge of operative forces. This problem has been approached by analysis of fluxes of isotopic species applied to opposite surfaces of a membrane. A simple and rather general flux ratio equation has been derived which may permit evaluation of membrane permeability, even without knowledge of forces, or of...

Journal: :Circulation 1999
A Hempel C Lindschau C Maasch M Mahn R Bychkov T Noll F C Luft H Haller

BACKGROUND Dihydropyridines block calcium channels; however, they also influence endothelial cells, which do not express calcium channels. We tested the hypothesis that nifedipine can prevent ischemia-induced endothelial permeability increases by inhibiting protein kinase C (PKC) in cultured porcine endothelial cells. METHODS AND RESULTS Ischemia was induced by potassium cyanide/deoxyglucose,...

Journal: :Investigative ophthalmology & visual science 2008
Owen A Anderson Timothy L Jackson Jasmin K Singh Ali A Hussain John Marshall

PURPOSE To quantify the permeability coefficient of albumin across human sclera and to assess topographical and age-related variation. METHODS Equatorial superotemporal scleral tissue from 15 donor eyes (mean age 60 years; range 39-84) was mounted in a modified Ussing chamber. Additional tissue was taken from the anterior and posterior superotemporal regions of six eyes, and equatorial supero...

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