A controlled clinical-pathologic study of peripheral arteriosclerotic gangrene is reported in which all amputated specimens were examined by a special technic of injection and dissection of the arteries. The type of patient in whom gangrene usually develops is defined. The effect of various clinical and pathologic conditions on the degree of arterial insufficiency is discussed from the viewpoin...

A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly s...

Gangrene of the extremities of venous origin is reviewed; it is a rare but distinct clinicopathologic entity hitherto not widely known. A classification of the cases of thrombophlebitis complicated with gangrene is presented, based on the presence of the peripheral pulses: (1) cases with palpable arteries; (2) cases with nonpalpable but patent arteries. Patency of the entire arterial system of ...