Serofendic acid is a low-molecular-weight compound extracted from fetal calf serum. We previously reported that intracerebroventricular administration of serofendic acid prevents cerebral ischemia-reperfusion injury. However, the effect of peripheral administration of serofendic acid on cerebral ischemia-reperfusion injury has not been examined. In the present study, we investigated the effect ...

The neurological manifestations of chronic hepatitis C is most often a peripheral sensory neuropathy characterised by numbness, burning and sensation of "pins and needles". Peripheral motor neuropathy, mononeuropathy, mononeuropathy multiplex and transverse myelitis also occur. Ischemic stroke and transient cerebral ischemia have also been reported. Anterior ischemic optic neuropathy is seen, o...

Chronic limb-threatening ischemia (CLTI) is a common condition with high rates of morbidity and mortality, as well racial, ethnic, socioeconomic, geographic disparities; however, process measures for CLTI care have not been developed. We developed the Limb threatening Ischemia Process PERformance (CLIPPER) cohort to create test quality CLTI. Using inpatient outpatient claims data from patients ...

A rat model of severe nerve ischemia was used to study the effects of ischemia and reperfusion on nerve conduction, blood flow, and the integrity of the blood-nerve barrier. Conduction failure was consistently found in the sciatic-tibial nerve during 1- and 3-hr ischemic periods. Recovery of the compound muscle action potential was prompt and complete upon reperfusion following 1 hr of ischemia...

there are confirmed beneficiary effects of exercise on atherosclerotic inflammation of ischemia-associated heart diseases. the purpose of this study was to evaluate the effect of aerobic exercise on t-regulatory cell markers of il-35 as well as foxp3 and t-helper2 marker of il-33 in patients with ischemic heart disease (ihd). this research was performed on 44 asymptomatic male patients with isc...

Contents 1. Introduction 2. Arterial disease 2.1. Surgery of carotid arteries 2.2. Arteries of aortic arch 2.3. Aneurysms in descending aorta. 2.4. Thoracoabdominal aneurysms. 2.5. Aneurysms of the abdominal aorta 2.6. Aneurysms of the peripheral arteries. 2.7. Surgical treatment of peripheral arterial occlusive disease (PAOD) 2.8. Acute limb ischemia 2.9. Arterial injuries 3. Venous diseases 3...

objective: to evaluate the efficacy and safety of intravenous and catheter directed thrombolysis by recombinant tissue plasminogen activator (alteplase) in the patients with non-traumatic acute limb ischemia (ali). methods: this was a randomized clinical trial being performed between 2009 and 2011 in mashhad university of medical sciences. we included those patients who were<75 years, with symp...

Clinical ergotism is a rare disorder, and clinical and therapeutic implications have continued to attract attention. The Holy Fire or St. Anthony's Fire was the primary vascular manifestation, causing burning pain and gangrene in the feet and hands related to the arterial spasm properties of ergot. The chronic use of ergotamine and migraine has also been associated with ergotism. Severe vasospa...

Superficial femoral artery (SFA) disease accounts for approximately 40% of the symptomatic peripheral arterial disease and remains a common cause of critical limb ischemia and lower-extremity amputation. Optical coherence tomography (OCT) has been extensively studied in the coronary circulation; however, its use in the peripheral arterial circulation is scarce. We present two cases of OCT use a...