BACKGROUND Identification of patients with acute coronary syndromes (ACS) among those who present to emergency departments with possible myocardial ischemia is difficult. Myocardial perfusion imaging with 99mTc sestamibi and measurement of serum cardiac troponin I (cTnI) both can identify patients with ACS. METHODS AND RESULTS Patients considered at low to moderate risk for ACS underwent gate...

Right ventricular apical pacing (RVAP) with a left bundle branch block on the electrocardiogram may result in regional wall motion abnormalities and decreased left ventricular function (LVF). Furthermore, perfusion defects in dipyridamole technetium-99m-methoxisobutylisonitrile ((99m)Tc-MIBI) myocardial perfusion imaging may occur despite a normal coronary angiogram. In a 68 years old patient, ...

Background Cardiac nuclear stress perfusion imaging is subject to artifact related to obesity, breast attenuation and diaphragm overlap. These factors are responsible for “false positive” results among patients undergoing evaluation for coronary atherosclerosis, leading to potentially unnecessary invasive coronary arteriography. Cardiac MRI adenosine stress perfusion imaging is unaffected by bo...

Abstract Stereotactic radiosurgery (SRS) is an established focal treatment for brain metastases with high local control rates. An important side-effect of SRS the development radionecrosis. On conventional MR imaging, radionecrosis and tumour progression often have similar appearances, but contrasting management approaches. Perfusion imaging used in post-treatment setting order to help distingu...

The fractal nature of heterogeneity of myocardial blood flow and its implications for the healthy and diseased heart is not yet understood. The main hindrance for investigation of blood flow heterogeneity and its role in physiology and pathophysiology is that conventional methods for determination of myocardial perfusion have severe limitations concerning temporal and spatial resolution and inv...

Background Combined assessment of wall motion from cine imaging and perfusion defects from first-pass perfusion (FPP) imaging has been shown to have a high diagnostic performance for detection of acute ischemia. In this setting, a single ungated CMR scan capable of simultaneously capturing perfusion deficits and wall motion abnormality can be useful for rapid diagnosis of ongoing acute ischemia...

Background Adenosine perfusion imaging at 1.5 Tesla (T) has been shown to yield good diagnostic values in comparison to quantitative coronary angiography. Perfusion imaging at 3 T has the potential benefit of higher contrastand signalto-noise ratios. However, little is known about diagnostic performance of 3 T perfusion imaging in comparison to 1.5 T and in comparison to invasive measurement of...

The concept of ultrafast echocardiographic imaging has been around for decades. However, only recent progress in ultrasound machine hardware and computer technology allowed to apply this echocardiography. High frame rate echocardiography can visualize phenomena that have never captured before. It enables a wide variety potential new applications, including shear wave imaging, speckle tracking, ...

osteomyelitis in childhood can be a challenging diagnosis. imaging plays an important role in the diagnosis of osteomyelitis in children, and the imaging findings are crucial in the treatment decision. pediatric hematogenous osteomyelitis may have variable radiological expression, which is influenced by the age and condition of the patient, the virulence of the causative agent, the stage of the...

Background Adenosine stress CMR perfusion imaging has numerous advantages over competing modalities for assessing CAD demonstrating high diagnostic and prognostic utility. However, adenosine stress CMR perfusion imaging is limited by motion-induced dark-rim artifacts (DRA) which may be mistaken for true perfusion abnormalities. We have previously demonstrated that a high-resolution variable-den...