The problem of emergence and dissemination of multidrug resistance, especially among Gram-negative bacteria, has reached alarming levels. This increases the need to develop surveillance methods that more effectively and accurately provide information about the emergence and spread of multidrug-resistant organisms. In this study, using a well-defined population of non-typhoidal Salmonella (NTS) ...

A simple, rapid, and environmentally friendly microextraction termed COU-2-D-μ-SPE has been developed for the analysis of three penicillins (i.e., oxacillin, cloxacillin, and dicloxacillin) in milk samples. An ordered mesoporous carbon, COU-2, was synthesized and used as the sorbent in dispersive micro-solid phase for the extraction of selected penicillins prior to high-performance liquid chrom...

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

OBJECTIVES To investigate effects on surveillance results of hospital antibiotic use when WHO defined daily doses (WHO DDDs) are adjusted to doses recommended for hospitalized patients [hospital-adjusted defined daily doses (haDDDs)]. METHODS Data for antibiotic use in 2006-11 for all 22 Norwegian Health Enterprises were analysed with both WHO DDDs and haDDDs as numerators. The haDDDs were de...

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...