نتایج جستجو برای: penicillin g acylase

تعداد نتایج: 453817  

Journal: :Protein engineering, design & selection : PEDS 2004
Wynand B L Alkema Charles M H Hensgens Harm J Snijder Evelien Keizer Bauke W Dijkstra Dick B Janssen

Penicillin acylase catalyses the condensation of Calpha-substituted phenylacetic acids with beta-lactam nucleophiles, producing semi-synthetic beta-lactam antibiotics. For efficient synthesis a low affinity for phenylacetic acid and a high affinity for Calpha-substituted phenylacetic acid derivatives is desirable. We made three active site mutants, alphaF146Y, betaF24A and alphaF146Y/betaF24A, ...

Journal: :jundishapur journal of microbiology 0
zohre ghanavi institute of standard and industrial research of iran, tehran, ir iran; institute of standard and industrial research of iran, tehran, ir iran. tel: +98-9125817046, fax: +98-2122431598 saeed mollayi young researchers and elites club, north tehran branch, islamic azad university, tehran, ir iran; young researches and elites club, north tehran branch, islamic azad university, tehran, ir iran, tel: +98-2122431598, fax: +98-2122431598 zahra eslami medicinal plants and drug research institute, shahid beheshti university tehran, iran

materials and methods samples were collected from six different farms and milk factories in iran, and were tested by beta-star and cylinder-plate methods. results among 992 raw milk samples, 236 positive samples, 9 suspected and 747 negative samples in respond to beta-star test and among 236 samples, which had positive responses to beta-star test, 28 positive, 0 suspected and 208 negative resul...

2011
Anne Holm Holger Mosbech

PURPOSE Patients with a history of allergic reaction to penicillin, but with no detectable specific IgE, are common and pose a dilemma. Challenge tests are considered to be the diagnostic gold standard. The aim of this study was to identify subgroups of patients with very low risk for reactions who could be safely tested using a more rapid and simple procedure. METHODS A total of 580 consecut...

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