Genotype-expression association analysis using linear regression may produce different test results depending on whether founders only or all pedigreed members are used. This difference is not due to the correlation of samples within a pedigree, because linear mixed models have been applied to account for that correlation. We investigated the possibility that the difference is due to a dependen...

Graphs (1-skeletons) of Traveling-Salesman-related polytopes have attracted a lot of attention. Pedigree polytopes are extensions of the classical Symmetric Traveling Salesman Problem polytopes (Arthanari 2000) whose graphs contain the TSP polytope graphs as spanning subgraphs (Arthanari 2013). Unlike TSP polytopes, Pedigree polytopes are not “symmetric”, e.g., their graphs are not vertex trans...

Inherited diseases commonly emerge within pedigree dog populations, often due to use of repeatedly bred carrier sire(s) within a small gene pool. Accurate family records are usually available making linkage analysis possible. However, there are many factors that are intrinsically difficult about collecting DNA and collating pedigree information from a large canine population. The keys to a succ...

This article discusses recent experiences with the Numeral Unit Spread Assessment Pedigree (NUSAP) system for multidimensional uncertainty assessment, based on four case studies that vary in complexity. We show that the NUSAP method is applicable not only to relatively simple calculation schemes but also to complex models in a meaningful way and that NUSAP is useful to assess not only parameter...

Abstract In forest tree breeding programs, open-pollinated families are frequently used to estimate genetic parameters and evaluate merit of individuals. However, the presence selfing events not documented in pedigree affects estimation these parameters. this study, 194 Eucalyptus globulus Labill. trees were compare precision estimated accuracies predicted values with conventional pedigree-base...

Synopsis High rank correlations existed between estimated breeding value for birth weight direct, weaning weight direct, postweaning gain direct, birth weight maternal, and weaning weight maternal from a genomicpolygenic model that used all phenotypic, pedigree, and genotypic information and a polygenic model. Variance components and genetic parameters from these two models were similar for all...

Recent advances in genomics resources and tools are facilitating quantitative trait locus mapping. We developed a crossbreed pedigree for mapping quantitative trait loci for hip dysplasia in dogs by crossing dysplastic Labrador Retrievers and normal Greyhounds. We show that one advantage to using a crossbreed pedigree is the increased marker informativeness in the backcross/F2 population relati...