Many recognize the phrase attached to title “The Times They Are A-Changin’” as name of 1964 record album by folk singer Bob Dylan.1 That seems like an appropriate way describe new phase percutaneous coronary intervention (PCI) delivery in United States and reason for a expert consensus statement on PCI without on-site surgical backup Society Cardiovascular Angiography & Interventions (SCAI).2 I...

Although percutaneous coronary intervention (PCI) has long surpassed coronary artery bypass grafting (CABG) as the most common revascularization strategy in patients with coronary artery disease [1], left main coronary artery disease (LMCD) is regarded a relative contraindication to PCI [2]. This lack of enthusiasm was related to studies showing that although balloon angioplasty was effective i...

ABBREVIATIONS IN THIS CHAPTER ACS Acute coronary syndrome BMS Bare metal stent CABG Coronary artery bypass grafting DAPT Dual antiplatelet therapy DES Drug-eluting stent GPI Glycoprotein IIb/IIIa inhibitor HIT Heparin-induced thrombocytopenia NSTE ACS Non–ST-segment elevation acute coronary syndrome PCI Percutaneous coronary intervention STEMI ST-segment elevation myocardial infarction UA Unsta...

BACKGROUND Several randomized controlled trials (RCT) have reported no difference in long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). The purpose of this pooled observational analysis was to compare recent retrospective studies examining long-term survival of patients with multi-vessel coronary artery disease undergoing CABG and PC...

Patients with chronic obstructive pulmonary disease (COPD) show a poor prognosis after myocardial infarction (MI) and percutaneous coronary intervention (PCI). We evaluated on-treatment platelet reactivity (PR) and several gene polymorphisms related to PR in 130 patients undergoing PCI with and without COPD. Those with concomitant COPD showed higher on-treatment PR values both at the time of PC...

We present a case of rescue percutaneous coronary intervention (PCI) using right radial approach in a rare case of single coronary artery originating from the right sinus. Although these anomalies and stenosis of anomalous vessels have earlier been reported, treatment of atherosclerotic lesions by PCI has rarely been reported. There is a definite risk during PCI in patients with a single corona...

Background: Frequent Percutaneous Coronary Intervention (PCI) procedures are being performed on a daily basis in Iran. However, no study has been reported on the current PCI practice in patients with acute coronary syndrome (ACS) in Iran. We aimed to describe the clinical characteristics and treatment patterns in Iranian ACS patients treated with PCI.    Methods: Between February 2017 and July...

R andomized, controlled trials (RCTs) comparing percutaneous coronary intervention (PCI) with coronary artery bypass graft (CABG) surgery for multivessel coronary artery disease (CAD) have routinely excluded patients with chronic kidney disease (CKD), so decisions about revascularization in this population depend on other sources of evidence (1). Several observational studies have reported that...

Coronary artery perforation (CAP) is a rare, but potentially serious complication of percutaneous coronary artery intervention (PCI). The strategies for management of patients with CAP include prolonged balloon inflation, coil embolization, covered stent implantation, pericardiocentesis, urgent surgery and reversal of heparin with protamine sulfate. We would like to share a case of type 3 perfo...

Abciximab is a widely studied glycoprotein IIb/IIIa inhibitor, specifically in the setting of patients undergoing percutaneous coronary intervention (PCI). The populations studied have included patients with non-ST-segment acute coronary syndromes, ST-segment elevation myocardial infarction, and elective PCI. This large amount of information provides a clear efficacy and safety profile of the d...