BACKGROUND Several ubiquitous polyhalogenated compounds (PHCs) have been shown to alter thyroid function in animal and in vitro studies. So far, epidemiologic studies have focused on the potential effect of a small number of them, namely, polychlorinated biphenyls (PCBs) and some organochlorines (OCs), without paying attention to other important PHCs. OBJECTIVES We investigated the relationsh...

We related total PCBs (t-PCBs) in white perch (Morone americana), an abundant estuarine resident that supports a valuable recreational and commercial fishery in the mid-Atlantic region, to the amount and spatial arrangement of developed land in watersheds that discharge into 14 subestuaries of Chesapeake Bay. We considered the intensity of development in watersheds using four developed land-use...

BACKGROUND Endometriosis is a common gynecologic disease characterized by the ectopic growth of endometrial tissue. In industrialized countries, it affects approximately 10% of women of reproductive age. Its etiology is unclear, but a multifactorial origin is considered to be most plausible. Environmental organochlorinated persistent pollutants, in particular dioxins and polychlorinated bipheny...

BACKGROUND Polychlorinated biphenyls (PCBs) are widely distributed environmental toxicants that contribute to numerous disease states. The main route of exposure to PCBs is through the gastrointestinal tract; however, little is known about the effects of PCBs on intestinal epithelial barrier functions. OBJECTIVE The aim of the present study was to address the hypothesis that highly chlorinate...

Concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) have been measured in fourteen sediment samples collected from leachate ponds, control wells, leachate treatment plants (LTPs), and a reference site of Benowo dumping site of Surabaya City, Indonesia. The PCBs and PBDEs were analyzed by gas chromatograph-mass spectrometer (GC-MS) using internal standar...

Fifty-five present and past transformer repair workers exposed to polychlorinated biphenyls (PCBs) and 56 unexposed comparison workers were evaluated in a clinical-epidemiologic study. The groups were similar in most demographic variables. Adipose tissue lipid and serum PCBs concentrations were higher in current exposed workers (geometric means adipose 2.1 ppm, serum 12.2 ppb). Concentrations i...

Among the environmental chemicals that may be able to disrupt the endocrine systems of animals and humans, the polychlorinated biphenyls (PCBs) are a chemical class of considerable concern. One possible mechanism by which PCBs may interfere with endocrine function is their ability to mimic natural hormones. These actions reflect a close relationship between the physicochemical properties encode...

Polychlorinated biphenyls (PCBs) are a group of chlorinated aromatic hydrocarbons that have attracted much public health attention. Having been used in industry since the 1930s, PCBs were found to be almost ubiquitous in the environment by 1966.' Owing to their excellent dielectric and insulating properties, PCBs have been used in transformers and capacitors, hydraulic systems, paints and other...

Fastidious anaerobic bacteria play critical roles in environmental bioremediation of halogenated compounds. However, their characterization and application have been largely impeded by difficulties in growing them in pure culture. Thus far, no pure culture has been reported to respire on the notorious polychlorinated biphenyls (PCBs), and functional genes responsible for PCB detoxification rema...

Printed circuit boards (PCBs) from antiquated electronic goods were processed by a pyrometallurgical route to produce and separate alloy slag phases. The process involved initial size reduction of PCBs, followed pyrolysis at 500 °C for 6 h finally smelting the solid materials in an electric furnace. A preliminary test was performed 1600 estimate composition generated. In later kilogram-scale ex...