A hybrid stochastic individual-based model of proliferating cells with chemotaxis is presented. The expressed by a branching diffusion process coupled to partial differential equation describing concentration chemotactic factor. It shown that in the hydrodynamic limit when number goes infinity converges solution nonconservative Patlak-Keller-Segel-type system. nonlinear mean-field defined and i...

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There is evidence that subtle breakdown of the blood-brain barrier (BBB) is a pathophysiological component of several diseases, including cerebral small vessel disease and some dementias. Dynamic contrast-enhanced MRI (DCE-MRI) combined with tracer kinetic modelling is widely used for assessing permeability and perfusion in brain tumours and body tissues where contrast agents readily accumulate...

Background: Skeletal muscle glucose utilization (SMGU) can be accessed by positron emission tomography (PET) and 18F-FDG to characterize insulin resistance. The quantity of skeletal muscle in the lumbar is sufficient to indicate that SMGU in the lumbar (SMGUlumbar) can be measured with 18F-FDG PET of the chest instead of obtaining thigh muscle SMGU (SMGU-thigh). This would reduce PET scan time ...

iii Acknowledgements iv Introduction  Data  Identifying the Spatial Pattern and its Dynamics  Methods  Results  Modelling the Spatial Pattern and its Dynamics  Methods  Results  Discussion  Conclusion  Literature Cited  tables . Summary information about the nine study plots  . Estimated parameters for the Poisson cluster processes  figures . Plot   . Plot   3. Pl...

We present a preliminary search for D-D mixing using the decays D → Kππ, additionally presenting Dalitz-plot distributions and a measurement of the branching ratio for this mode. A new tagging technique is used to produce the doubly Cabibbo-suppressed Dalitz plot, which in turn is used to motivate the method used for the D-mixing search. We analyze 230.4 fb of data collected from the BABAR dete...

When creating interactive drama computer games then it is frequently useful to be able to generate a plot to use as a background for the drama and to use as a knowledge base for Non-Player Characters. In this article a new engine is proposed that dynamically creates new game plots for a murder mystery based game. The game engine uses Bayesian networks to create a new plot based on a probability...

The authors developed and tested a method for the noninvasive quantification of the cerebral metabolic rate for glucose (CMRglc) using positron emission tomography (PET), 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function. Dynamic PET data acquired 12 to 48 seconds after rapid tracer injection were summed to identify carotid artery regions of interest (ROIs). The ...