The aim of the present study was to establish to what degree a one-year exposure of rat females to 5, 50 and 100 mg of Cd/l affects cell morphology of the submandibular glands. After one-year cadmium exposure of female rats, at doses of 5, 50 and 100 mg Cd/l, a pathomorphological examination revealed periductal fibrosis in the submandibular glands of rats in all the three experimental groups, w...

Background: Hemorrhagic fever with renal syndrome (HFRS) is a viral, natural focal infection that currently relevant for many countries of the world and ranks high among zoonotic viral infections in Russian Federation. The purpose our work was to present main stages discovery study HFRS: from registration first clinical cases disease by military doctors east country current level research. Mate...

The last decade is characterized by significant progress in the treatment of rectal cancer (reduction number relapses to 5–6 % with use prolonged radiation therapy) before surgery. greatest success has been achieved lower ampulla rectum, when it possible develop a complete clinical response tumor chemoradiotherapy. Nevertheless, requirement issues improve results upper and middle ampullar rectu...

BACKGROUND: The histopathological characteristics of cholesteatoma are hyperproliferation and differentiation of the epithelium. The proliferative capacity of cholesteatoma was studied through the kinetics of the epithelium of cholesteatoma. The present study was undertaken to compare the rate of proliferation and apoptosis using immunohistochemistry with PCNA antigen and p53 protein in cholest...

Objective - to study the histochemical and histological features of liver lungtissues in patients with non-alcoholic steatohepatitis (NASH) obesity under conditionof a comorbid course chronic obstructive pulmonary disease (COPD).Material methods. The autopsy material 27 cases NASH, including 13 casesof NASH I degree (group 1), 14 withcomorbid COPD II-III stage 2) was used. groups comparison inc...

The thymus is now considered a derivative of the immune system being, to greater extent, its central organ. Immunodeficiency states and dysregulation also depend on quality thymus, which may be determined both genetically by fetopathic approach as well due possibility mode intravital injuries, age-related involution over different periods life. Not accidentally, there are various morphometric b...

Geometric abnormalities of the human hip joint, as found in femoroacetabular impingement (FAI) and acetabular dysplasia, alter hip biomechanics and may be the primary causes of osteoarthritis in young adults. However, empirical evidence of direct correlations between abnormal geometry, altered biomechanics, and osteoarthritis is scarce. Also, clinical measures used to diagnose FAI and dysplasia...

The literature on the neuropathology of bipolar disorder (BD) is reviewed. Postmortem findings in the areas of pathomorphology, signal transduction, neuropeptides, neurotransmitters, cell adhesion molecules, and synaptic proteins are considered. Decreased glial numbers and density in both BD and major depressive disorder (MDD) have been reported, whereas cortical neuron counts were not differen...