Saprophytic leptospires are spirochetes enclosed within the non-pathogenic clade of genus Leptospira, which in turn is subdivided into two subclades S1 and S2. To date, microorganisms included these have been isolated from environment various parts world, believed to no known animal reservoirs. After a case Leptospira interrogans serovar Pomona was notified owner farm Sardinia, all animals (11 ...

Canine leptospirosis is a bacterial disease caused by spirochetes of the genus Leptospira. Infections can vary from asymptomatic and chronic infections to clinical acute diseases. The endemic in tropical areas, such as Latin American countries, but broad understanding dynamics circulation strains, based on molecular data, has not yet been performed. Based silico analyses, present study aims ana...

Efficacy of primers capable of amplifying conserved outer membrane protein (OMP) genes i.e., lipL21 and lipL32 of Leptospira strains was tested for rapid and early diagnosis of the leptospirosis using a polymerase chain reaction (PCR). These OMP genes were found to be conserved in various leptospiral serovars viz., Canicola, Pomona, Icterohaemorrhagiae, Pyrogenes, Sejroe, Grippotyphosa, Ballum ...

Argentin 1 1.2 X Australin 1 1.2 0.2 Barbados 17 12 23.6 Brazil 10 18 0.8 France 24 2 X Guadeloupe/Martiniq 12 3.9 13.7 Netherland 5 23 4.9 New 8 77.4 2.6 Russian 2 1.05 X US 1 4.3 1.5 But what means « leptospirosis » ? Leptospirosis is induced by pathogenic Spirochaetales, belonging to the genus Leptospira. Now this genus is divided in several genomospecies : at least 7 for the pathogenic stra...

Leptospirosis is an important zoonotic disease in the world and a real public health concern for many years in New Caledonia. A cross-sectional survey was carried out on domestic and wild animals from New Caledonia in April 2009. Blood samples were collected from 30 cattle, 29 deers, (Cervus timorensis russa), 25 horses, 51 dogs, and 8 cats and were tested for 23 serovars of pathogenic Leptospi...

BACKGROUND Leptospires are presumed to enter their host via small abrasions or breaches of the skin. The intraperitoneal route, although commonly used in guinea pig and hamster models of leptospirosis, does not reflect conditions encountered during natural infection. The aim of this study is to develop a novel leptospirosis guinea pig model through epicutaneous route and to elucidate the pathog...

Pathogenic Leptospira transmits from animals to humans, causing the zoonotic life-threatening infection called leptospirosis. This infection is reported worldwide with higher risk in tropical regions. Symptoms of leptospirosis range from mild illness to severe illness such as liver damage, kidney failure, respiratory distress, meningitis, and fatal hemorrhagic disease. Invasive species of Lepto...

Leptospirosis is a neglected zoonosis caused by pathogenic Leptospira. In this study, we characterized the virulence of isolate B3-13S obtained from a wild mouse (Mus musculus) captured in New Caledonia, subsequently identified as a bacterium belonging to the L. borgpetersenii serogroup Ballum. Hamsters were infected with an intraperitoneal injection of 2 × 10(8) bacteria, resulting in severe h...

Spiral filaments seen in the blood cultures of two patients with fever and jaundice were initially thought to be leptospires; these were later proved to be artefacts. An investigation was carried out to exclude the possibility of laboratory contamination of the culture media and to find out how these objects were produced. The significance of the findings is discussed in relation to the possibi...