Cells of Candida parapsilosis were extracted sequentially with different organic solvents. The sodium carbonate wash of the methanol extract showed carcinogenic activity in mice as demonstrated by the appearance of 6 sarcomas at the site of injection in a group of 16 animals. Suggestive carcinogenic activity in the appearance of subcutaneous sarcomas and increased frequency of leukemias and pul...

A fast development of a wide variety of proteomic techniques supported by mass spectrometry coupled with high performance liquid chromatography has been observed in recent years. It significantly contributes to the progress in research on the cell wall, very important part of the cells of pathogenic fungi. This complicated structure composed of different polysaccharides, proteins, lipids and me...

Background and Objective: The endophytes are the fungi or bacteria that live within a plant in a symbiotic relationship. This study aimed to investigate the effect of isolated bacterial endophytes from Allium jesdianum on some bacterial pathogens such as Staphylococcus aureus, Escherichia coli as well as pathogenic fungi, including Trichophyton mentagrophytes and Candida albicans. Materials an...

Genomic imbalance resulting from aneuploidy is detrimental to the proliferation of cells in conditions suitable for normal growth and differentiation [1,2]. However, there is growing evidence that aneuploidy confers a significant growth advantage when cells undergo severe genetic or environmental perturbations [3–6]. For example, aneuploidy restored the ability to proliferate in yeast cells tha...

This special issue, "Genomic Data in Pathogenic Fungi," focuses on the genomics of human and plant pathogens. Efforts like this are important because so little information about these organisms is available.[...].

Recent interest in the relationship of fungi to human disease, both as infecting agents and as incitants of phenomena of hypersensitivity, induced us to undertake a detailed study of a patient who presents an uncommon skin lesion which appears to be associated with sensitivity to at least six species of non-pathogenic fungi. Passive transfer antibodies for these fungi were present in the patien...