UNLABELLED During the past decade, evidence has emerged that statins have neuroprotective effects. AIM The aim of this study was to investigate the effects of atorvastatin and rosuvastatin on learning and memory in rats with diazepam-induced amnesia. MATERIAL AND METHODS Experiments were carried out on 48 white male Wistar rats, divided into 6 groups, each of 8 rats. The experimental animal...

Effects of pre- and post-natal undernutrition on learning and memory parameters were studied in albino rats. Prenatal undernutrition was induced in rat pups by restricting the mother's diet by 50% during the entire gestation period, whereas postnatal undernutrition was induced in rat pups by restriction of their diet by rotating them between lactating and non-lactating maternalised females for ...

We examined the effect of the acetylcholinesterase (AChE) inhibitor, donepezil hydrocloride (DONP), on group II metabotropic glutamate (mGlu) receptor agonist- or antagonist-induced amnesia in the step-through passive avoidance task in male mice. DCG-IV, a group II mGlu receptor agonist, at dose of 50 ng and LY341495, a group II mGlu receptor antagonist, at dose of 300 ng, significantly attenua...

objective: estrogen deficit following menopause results in cognitive behaviors impairment. severity of these impairments in menopause women suffer with cerebral hypo perfusion/ischemia (hi) cause the brain damage and neuronal death. this study aimed to evaluate the effects of pomegranate seed extract (pgse) on avoidance memories after permanent bilateral common carotid arteries occlusion (2ccao...